102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
60 citations,
June 1997 in “Baillière's clinical obstetrics and gynaecology” PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
9 citations,
March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
5 citations,
October 2021 in “Clinical, cosmetic and investigational dermatology” Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
16 citations,
September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
8 citations,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
August 2023 in “MOJ women's health” Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
October 2022 in “Frontiers in Endocrinology” New tools show that in fish, NPY increases feeding and somatostatin decreases it.
207 citations,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
89 citations,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
75 citations,
September 2009 in “Dermato-endocrinology” The skin produces and processes hormones, affecting both local and overall body functions.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
54 citations,
October 2010 in “Clinics in dermatology” Diet, especially dairy and high-sugar foods, can cause acne.
36 citations,
June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
9 citations,
December 2022 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
9 citations,
August 2021 in “Experimental dermatology” Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
9 citations,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
7 citations,
January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
1 citations,
December 2022 in “Biomedicines” Middle-aged women with PCOS often continue to experience symptoms related to high androgen levels, like unwanted hair growth.
1 citations,
August 2022 in “Veterinary medicine and science” The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
January 2024 in “Medicina” Statins may help treat PCOS by lowering androgen levels and improving cholesterol.
August 2023 in “Journal of Clinical Medicine” Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.
Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.
Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.
January 2025 in “Journal of Clinical Medicine” PCOS is the most common cause of hirsutism, and personalized treatment is important.
January 2018 in “Biomedical Research (Aligarh)” Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.
January 2020 in “Brazilian Journal of Pharmaceutical Sciences” Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.
19 citations,
May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.