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Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

DHT affects testicular development and regulates spermatogenesis in some fish.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Sex hormones affect brain injury differently in males and females.

Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Hormones and genes affect hair growth and male baldness.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A woman with severe angioedema improved significantly after treatment with rituximab.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Sex steroids affect the MafB gene differently in male and female hamsters.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.