research Interferon-24 Regulates the Expression of MMP1 and Dermal Collagen of the Skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
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research Cryo-EM and Molecular Dynamics of TRPV3 Channel in Activated State Reveal Structural Features Implicated in Severe Itch and Hyperkeratosis
The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
research DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes
DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
research Inflammation, Stem Cells and Wound Healing in Skin Aging
Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
research Ocular Manifestation in Progeria: A Case Report
A boy with progeria had eye problems and signs of aging like hair loss and skin wrinkling.
research Successful Allogeneic Epidermal Grafting of Chronic Recessive Dystrophic Epidermolysis Bullosa Wounds from Hematopoietic Cell Donors in the Outpatient Setting
Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Changes in the Aging Dermal Hair Follicle Environment in Female Scalp
Aging causes changes in scalp cells that can negatively affect hair health.
research A Prospective Study of Daylight Photodynamic Therapy for Treatment of Actinic Keratoses in an Irish Population
Daylight photodynamic therapy is effective and well-tolerated for treating actinic keratoses with minimal side effects.
research Faculty Opinions Recommendation of Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells
Activating telomerase can boost hair follicle stem cell growth and hair production.
research The Prevalence of Itch and Pain and Its Characteristics in Patients with Mild to Moderate Venous Insufficiency and Its Relationship to the Degree of Venous Insufficiency
Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.
research Prevalence of Itch and Pain in Patients with Mild to Moderate Chronic Venous Insufficiency at Parkland Memorial Hospital (2005)
Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia
Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
research Cultured Human Foreskin as a Model System for Evaluating Ionizing Radiation-Induced Skin Injury
Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
research LncRNA-miRNA-mRNA Regulatory Networks in Skin Aging and Therapeutic Potentials
ceRNA networks offer potential treatments for skin aging and wound healing.
research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Punch Hair Grafting Methods
The document recommends careful planning and techniques for successful punch hair grafting in hair restoration.
research Decision Letter: Dynamics of Nevus Development Implicate Cell Cooperation in the Growth Arrest of Transformed Melanocytes
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
research Editor Bids Adieu
The Editor-in-Chief is proud of the journal's growth and improvements during his term and optimistic about its future.
research Sensitive Skin
Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
research Trichodynia: A Review of the Literature
Trichodynia is a painful scalp condition linked to hair loss and inflammation, often with anxiety, affecting more women and needing better treatment options.
research Sensitive Skin
Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
research Effect of Minoxidil on Pre- and Postconfluent Keratinocytes
Minoxidil prolongs cell life, slows aging, and may produce longer hairs.
research Trichodynia Revisited
Trichodynia is a painful scalp condition not directly linked to the amount or type of hair loss and may involve psychological factors, with treatments showing mixed results.
research Scalp Neuropathy in Androgenetic Alopecia
Scalp nerve issues are linked to hair loss in men.
research The Specification Of Merkel Cell In The Back Skin And Glabrous Paw Skin Is Controlled By FGFR2-Mediated Signaling
FGFR2 signaling controls Merkel cell formation in different skin regions.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Scalp Dysesthesia Related to Cervical Spine Disease
Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.