Synergism Between Tocotrienol and Injectable Platelet-Rich Fibrin in Hair Follicle Stem Cells Proliferation: An In Vitro Study

    Murtaza Mohemadali Contractor, Kalyani Bhate, Supriya Kheur, Avinash Kharat, Sherwin Samuel, Manoj Kumar U
    Image of study
    TLDR Aloe Vera and injectable platelet-rich fibrin (i-PRF) together can speed up and improve hair growth when used in the right amounts.
    The in-vitro study aimed to evaluate the synergism between Aloe Vera and injectable platelet-rich fibrin (i-PRF) in the treatment of Androgenic Alopecia (AGA). Hair follicle-derived stem cells (HFSCs) from an individual with AGA were exposed to different concentrations of Aloe Vera, i-PRF, and a combination of both. Results showed that Aloe Vera increased HFSCs proliferation up to a certain concentration, after which cell senescence occurred. i-PRF demonstrated a direct relationship between concentration and cell proliferation. Notably, a specific concentration of the combination treatment resulted in double the cell proliferation compared to the other groups. The study concluded that adjunct therapy, when incorporated into standard treatment, results in faster and better hair growth, emphasizing the importance of optimizing product concentration.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 29 results

      community Interesting anecdote regarding TOPICAL vitamin e

      in Research/Science  23 upvotes 1 year ago
      A user accidentally discovered that applying vitamin E oil to their scalp significantly reduced their hair shedding for about 1.5 weeks. They reported improved hair quality and a drastic decrease in hair loss after treatment.

      community Vitamin E

       20 upvotes 5 years ago
      Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 6 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

    Related Research

    4 / 4 results