June 2026 in “Lahore Garrison University Journal of Life Sciences” In this preliminary study, selenium-resistant bacteria and selenium-treated pea sprout extracts showed minimal inhibitory effects on the dandruff-associated fungus Malassezia furfur compared to controls, suggesting potential for further investigation.
February 2026 in “Pakistan Veterinary Journal” In this study of White cashmere goat ewes and their offspring in Tibet, selenium and vitamin E supplementation improved antioxidant capacity and serum biochemical indices and enhanced secondary hair follicle development in lambs, but did not significantly alter fecal microbiota composition.
January 2026 in “SHILAP Revista de lepidopterología” In this study, researchers highlight the importance of correcting selenium and zinc deficiencies as part of a comprehensive management strategy for patients with autoimmune thyroiditis complicated by alopecia, as these elements play key roles in thyroid hormone biosynthesis and hair follicle function.
January 2026 in “Dermatologic Therapy” This study found that a shampoo containing 1% selenium sulfide and 1% salicylic acid significantly improved the clinical signs and symptoms of seborrheic dermatitis and dandruff over an 8-week period.
September 2025 in “Clinical Toxicology” In this investigation, acute alopecia was linked to selenium-contaminated wheat in rural Maharashtra, India, following reports of sudden hair loss in 18 villages, with evaluations conducted in Machindrakhed and Bhondgaon.
This research highlights selenium's critical roles in various biological processes and underscores the potential health impacts of both its deficiency and excess, including increased mortality risk, poor immune function, and neurological issues.
September 2025 in “ACS Applied Polymer Materials” This study reported that a composite hydrogel made with Chlorella-derived extracellular polysaccharide–selenium nanoparticles showed strong antibacterial and anti-inflammatory effects in vitro and significantly accelerated wound healing in vivo, offering potential for managing infected wounds and monitoring healing progression.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a novel hydrogel combining Chlorella extracellular polysaccharide–selenium nanoparticles (EPS-SeNPs) with biocompatible components, which demonstrated strong antibacterial and anti-inflammatory effects, significantly accelerating wound healing in an infected rat model, and enabling pH-based monitoring of healing.
In this study, women with acute telogen effluvium taking the Hair’InsideTM supplement for 84 days showed significant improvements in hair regrowth, shedding, brightness, and volume compared to placebo, with no reported adverse effects.
July 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This review investigates how selenium, a trace element found in wheat, may impact hair health by examining its biochemical role in hair follicle biology and its potential therapeutic and toxicological effects.
May 2025 in “Journal of Dermatological Treatment” This study found that a medicated shampoo containing selenium sulfide and salicylic acid effectively reduced symptoms of seborrheic dermatitis in Chinese patients, but females experienced significantly lower rates of good effectiveness and tolerance compared to males.
March 2025 in “Skin Appendage Disorders” In this study, selenium disulfide shampoo was found to reduce dandruff severity and rebalance the scalp microbiome in individuals with all hair types experiencing moderate to severe dandruff, with subjects reporting high satisfaction and good tolerance over a 6-week period.
March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
September 2024 in “Journal of the American Academy of Dermatology” This introduction highlights that a common challenge with managing dandruff, a mild form of seborrheic dermatitis, is compliance with treatment, and notes that selenium disulfide shampoo is beneficial for this condition.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
April 2024 in “Research Square (Research Square)” In this randomized trial, lupus patients taking daily 200 μg selenium supplements for eight weeks showed significant improvements in metabolic markers like CRP, ESR, MDA, and GPX, as well as reduced clinical symptoms such as arthritis and alopecia, compared to those receiving a placebo.
February 2024 in “Exposure and Health” Selenium supplements may reduce mercury levels in the hair of city dwellers in China.
February 2024 in “Journal of Geochemical Exploration” Selenium levels in soil, crops, and human hair in Northwest China are within safe limits.
February 2024 in “Animals” This study found that supplementing pregnant Hanshan white cashmere goats' diets with selenium yeast led to higher birth weights, improved cashmere quality and yield, and enhanced hair follicle development in their offspring, possibly through increased antioxidant capacity.
October 2023 in “Èkologiâ čeloveka” People in Moldova have less selenium in their hair than recommended, which may contribute to hair loss.
September 2023 in “Food and chemical toxicology” In this study on Sprague-Dawley rats, 0.60 mg/kg doses of L-Se-methylselenocysteine and sodium selenite were associated with liver toxicity and reduced sperm motility, while Se-enriched peptides showed no observable adverse effects up to 0.60 mg/kg.
June 2023 in “Skin Research and Technology” The researchers reported that an oral supplement containing hydrolysed fish-origin collagen, taurine, cysteine, methionine, iron, and selenium significantly improved the effectiveness of anti-hair loss treatments in people with androgenic alopecia or chronic telogen effluvium after 12 weeks, compared to drug treatments alone.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
February 2023 in “European journal of geriatrics and gerontology” Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.
January 2021 in “Agrobiological records” This review paper examined recent research on the biofortification of horticultural plants, such as fruits and vegetables, with selenium, highlighting their role in addressing selenium deficiencies and supporting various biological functions crucial to human health.
This study found that four bacterial isolates from a microbiology laboratory collection demonstrated resistance to selenate, with molecular analysis showing they closely resemble different strains of Bacillus megaterium.
The levels of zinc, vitamin D, ferritin, and selenium are different in people with androgenic alopecia compared to a control group.
January 2018 in “ScholarWorks @UVM (University of Vermont)” This study provides evidence supporting the theory that the presence of selenocysteine in proteins, such as thioredoxin reductase, may confer chemical reversibility, which contributes to their oxidative resistance and potential catalytic functions.
April 2017 in “The FASEB journal” This study suggests that selenium deprivation in mice accelerates age-related degeneration but paradoxically promotes longevity, potentially decoupling healthspan from lifespan.
April 2015 in “The FASEB Journal” This study suggests that selenium deficiency accelerates aging-related health deterioration in mice with short telomeres, providing a model for exploring selenium’s role in human aging.