Effects of Selenium and Other Micronutrient Intake on Human Health
September 2025
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Studysummary This research highlights selenium's critical roles in various biological processes and underscores the potential health impacts of both its deficiency and excess, including increased mortality risk, poor immune function, and neurological issues.
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Selenium is a crucial microelement involved in various homeostatic processes through selenoproteins, impacting immune response, cellular redox state, and central nervous system development. However, both selenium deficiency and excess can adversely affect health. Deficiency is linked to increased mortality risk, poor immune function, and diseases like Keshan disease and cognitive decline. Excess selenium can cause hair loss, dermatitis, and increase the risk of type 2 diabetes and neurological issues. The narrow safe dose range of selenium makes it a significant focus of research, alongside other micronutrients, for its impact on human health.