39 citations
,
January 2019 in “Journal of Dermatological Treatment” This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.
30 citations
,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” This study found that lowering serum DHT levels with 5 mg finasteride daily did not significantly alter serum gonadotropin levels in healthy young men after 28 days.
15 citations
,
September 2013 in “Pharmaceutical Biology” This study found that Zizyphus jujuba fruit aqueous extract may reduce nephrotoxicity caused by ibuprofen in rats by lowering serum urea and creatinine and improving kidney antioxidant enzyme activities.
November 2023 in “JAAD case reports” This research indicates that androgens may drive hidradenitis suppurativa in some patients, as they show higher testosterone levels compared to nonaffected controls, and testosterone-lowering medications are established treatments for milder cases.
8 citations
,
November 1978 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, cyproterone acetate was found to be effective in treating 'idiopathic' hirsutism, while a combination of ethinyloestradiol and lynoestrenol reduced hair growth in fewer patients despite uniformly lowering testosterone levels.
May 2019 in “Gastroenterology” Androgen lowering medications don't significantly change HCV-related liver cancer risk in men.
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills help treat acne, especially when caused by excess male hormones, and are safe to use with antibiotics.
May 2023 in “Research Square (Research Square)” In this study, researchers observed that treatment with Agaricus subrufescens ethanolic extract improved blood glucose, testosterone levels, and menstrual irregularity in rat models of letrozole-induced Polycystic Ovarian Syndrome, also noting a decrease in elevated liver and ovary weights, suggesting protective effects on renal function.
50 citations
,
May 2018 in “International journal of cardiology” This study found associations between genetic predictors of increased testosterone and cardiovascular risk factors, but the implications for testosterone supplementation are unclear due to uncertainties in genetic variant functions.
408 citations
,
May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that dutasteride more effectively reduced serum dihydrotestosterone levels than finasteride in patients with benign prostatic hyperplasia.
April 2026 in “International Journal of Research and Review” This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.
24 citations
,
February 2023 in “BMC Complementary Medicine and Therapies” This study found that Forsythiaside A may protect against sepsis-induced acute kidney injury in mice by reducing inflammation and apoptosis through modulation of ER stress responses.
June 2017 in “Journal of clinical and investigative dermatology” This article reviews the genetic associations between MTHFR mutations, homocysteine levels, and autoimmune diseases, without reporting new experimental results.
This article reviews the synthesis and properties of isotretinoin, tazarotene, minoxidil, and finasteride, and reports no new findings.
August 2025 in “Nanomaterials” This study found that tea polyphenol–zinc significantly improved intestinal barrier function and reduced liver inflammation and oxidative stress in mice with diquat-induced damage.
114 citations
,
March 2018 in “PLOS Medicine” This study found that women with polycystic ovary syndrome have higher rates of nonalcoholic fatty liver disease, with androgen excess contributing to the risk.
26 citations
,
May 2021 in “International Journal of Molecular Sciences” In this review, researchers examined the physiological benefits of Cheonggukjang, a salt-free fermented soybean paste, highlighting its various health-promoting components that may contribute to improved heart health, diabetes management, and cancer prevention, among other benefits.
39 citations
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September 2000 in “Obstetrics and Gynecology Clinics of North America” This article reviews evidence on hyperinsulinemia and insulin resistance in women with polycystic ovary syndrome and evaluates therapeutic responses to insulin-lowering agents, reporting no new clinical findings.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.
506 citations
,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.
11 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
10 citations
,
February 2008 in “International Journal of Andrology” This study found that a 400-mg dose of oral testosterone with dutasteride increases serum testosterone levels for 8–10 hours in hypogonadal men, with the nanomilled formulation unaffected by food, suggesting a practical twice-daily therapy option.
8 citations
,
June 2020 in “International Journal of Dermatology” This study found a significant correlation between vitamin D deficiency and the severity of androgenetic alopecia in males, suggesting that vitamin D may influence the condition's premature onset.
5 citations
,
April 2021 in “Journal of Endocrinological Investigation” This study concluded that among men with normal testosterone levels, a small increase in serum dihydrotestosterone may reduce symptoms of hypogonadism, suggesting its potential diagnostic use after ruling out hypogonadism.
1 citations
,
October 2024 in “Cureus” This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.
1 citations
,
April 2015 in “Journal of Dermatology and Dermatologic Surgery” This study found higher serum prolactin levels in patients with psoriasis, vitiligo, and alopecia areata compared to controls, and prolactin levels correlated with disease severity in psoriasis and alopecia areata but not vitiligo.
October 2025 in “International Journal of Social health” This systematic review reported that among men taking finasteride for benign prostatic hyperplasia, total PSA levels decreased by 30% to 50%, and free PSA by up to 45%, with reductions in prostate volume and PSA density observed as well.
This study developed and tested a polyherbal anti-dandruff hair serum using natural ingredients with antifungal, anti-inflammatory, and conditioning properties, reporting notable antifungal efficacy, good stability, and satisfactory physicochemical characteristics, suggesting the serum is a safe and effective natural alternative for daily dandruff treatment.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” In this study, elevated afamin concentrations were associated with metabolic syndrome in young women, particularly those with insulin resistance, suggesting a potential predictive role for afamin in metabolic risk assessment.
August 2025 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion-based hair serum containing M. oleifera seed oil, which maintained its physical characteristics and reduced the oil's sticky texture, making it more suitable for hair loss treatment compared to traditional formulations.