Tea Polyphenol–Zinc Nanocomplexes Alleviate Diquat-Induced Liver and Small Intestine Oxidative Stress in C57BL/6 Mice

    August 2025 in “ Nanomaterials ”
    Tingting Liu, Yang Zhao, Jie Feng
    TLDR Tea polyphenol–zinc helps protect the liver and intestines from oxidative stress.
    The study examined the effects of tea polyphenol–zinc nanocomplexes (Tp-Zn) on diquat-induced oxidative stress in C57BL/6 mice, involving 5 groups of 6 mice each. Tp-Zn significantly reduced oxidative stress in the liver and small intestine by enhancing antioxidant enzyme activities and reducing oxidative damage markers. It improved liver function by lowering serum levels of AST, ALT, and AKP, and enhanced intestinal barrier integrity by upregulating tight junction proteins. The protective effects are likely mediated through the activation of the Nrf2 signaling pathway, suggesting Tp-Zn as a promising therapeutic agent for oxidative stress-related conditions.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 332 results

      community Natural Remedies: Polyphenols and Hair Loss

       21 upvotes 6 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  735 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Foods with sufficient procyanidin b2?

      in Treatment  6 upvotes 4 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Conversation focuses on foods with sufficient procyanidin b2, such as dark chocolate and apples, and the required dosage.

      community DHT blocking ingredients

      in Treatment  6 upvotes 4 years ago
      The conversation discusses DHT blocking treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and organic flaxseed oil containing omega-3 fatty acids. It highlights skepticism about alternative treatments and emphasizes the proven effectiveness of Finasteride and Dutasteride.

    Similar Research

    5 / 1000+ results