Red Blood Cell Folate Level in Patients with Alopecia Areata

The document discussed the potential genetic association between methylenetetrahydrofolate reductase (MTHFR) mutations and autoimmune disorders, including alopecia areata. It highlighted that folate plays a crucial role in producing antioxidant effects and lowering homocysteine levels, which are important for the methylation cycle. The study provided average serum and red blood cell folate concentrations for men and women, noting that red blood cell folate levels are more reliable indicators of long-term folate status as they are not influenced by external factors like diet and drugs.