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research MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case-Control Study

June 2021 in “The American Journal of the Medical Sciences”

Androgenetic alopecia is linked to a higher risk of coronary heart disease due to certain genetic factors and high homocysteine levels.

research Methylenetetrahydrofolate Reductase C677T Mutation in Patients with Alopecia Areata in Turkish Population

15 citations, August 2013 in “Gene”

The MTHFR C677T mutation may increase the risk of alopecia areata in the Turkish population.

research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

5 citations, September 2018 in “International journal of genomics”

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

research Red Blood Cell Folate Level in Patients with Alopecia Areata

June 2017 in “Journal of clinical and investigative dermatology”

Red blood cell folate levels are reliable indicators of long-term folate status in alopecia areata patients.

research A Study on the Clinical Profile and Pharmacogenetics of Methotrexate Treatment in Patients with Rheumatoid Arthritis

April 2014

The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.

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Community Join

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community Is anyone taking creatine while on fin and/or dut?

in Finasteride/Dutasteride 33 upvotes 5 months ago

The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.

community Sharing what worked for me (PCOS related hair loss)

in Female 33 upvotes 11 months ago

A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.

community 3 years on Dutasteride and still thinning - what would the next logical step be?

in Finasteride/Dutasteride 24 upvotes 3 weeks ago

The user is experiencing hair thinning despite using Dutasteride and Finasteride and is considering adding Minoxidil. Suggestions include increasing the Dutasteride dose, checking for health issues, and considering a hair transplant.

community Can low level of vitamins cause hair loss?

in Research/Science 22 upvotes 1 year ago

The conversation is about whether low vitamin levels can cause hair loss. The consensus is that the user's vitamin levels are normal and unlikely to affect hair loss or the effectiveness of finasteride and minoxidil treatments.

community Can a folate deficiency make androgenetic alopecia worse?

in Treatment 1 upvotes 11 months ago

The user is treating androgenetic alopecia with finasteride and discovered a folic acid deficiency. They are asking if curing the deficiency can worsen or improve their hair condition.

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