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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Hair follicle cells can help heal wounds and study skin diseases.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.

Hair color is determined by melanin produced and transferred in hair follicles.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The hair oil may effectively treat common hair problems with fewer side effects.

Graying hair happens due to aging and might be delayed by new treatments.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

Estrogens and progesterone are key in regulating melasma pigmentation.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.

Neuregulin3 affects cell development in the skin and mammary glands.

FUE is a less invasive hair restoration method with potential to become standard, offering benefits like reduced scarring and pain, but requires experience to minimize risks.

Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.