9 citations,
April 2019 in “International Journal of Molecular Sciences” Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
8 citations,
June 2012 in “PloS one” Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
7 citations,
March 2021 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
7 citations,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
7 citations,
April 2014 in “Cell biology international” Melatonin treatment helps improve skin health in postmenopausal rats.
6 citations,
April 2020 in “Applied sciences” Hair growth medium helps heal wounds and regrow hair in mice.
6 citations,
July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
6 citations,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
6 citations,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
5 citations,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
4 citations,
August 2023 in “Nature Communications” Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.
4 citations,
December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
4 citations,
August 2020 in “Applied Materials Today” Hydrogel microcapsules help create cells that boost hair growth.
4 citations,
July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
3 citations,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
2 citations,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
2 citations,
November 2022 in “Scientific reports” Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
2 citations,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
2 citations,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
2 citations,
January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
1 citations,
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
1 citations,
March 2021 in “Dermatological reviews” AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
1 citations,
November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
1 citations,
November 2018 in “Therapeutic Delivery” New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
1 citations,
November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.