At the Dawn of Hair Research – Testing the Limits of Hair Follicle Regeneration

    February 2014 in “ Experimental Dermatology ”
    Maksim V. Plikus
    Studysummary This review discusses the potential for cellular hair regeneration by building on foundational rodent studies and emphasizes the need for protocols to enhance the inductive properties of human dermal papilla cells.
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    Research cited in this study 13

    1. Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells Nature communications · 2014
    2. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    3. Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach Journal of Investigative Dermatology · 2013
    4. Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal-Epidermal Composites Journal of Investigative Dermatology · 2013
    5. Morphogenesis of Chimeric Hair Follicles in Engineered Skin Substitutes With Human Keratinocytes and Murine Dermal Papilla Cells Experimental Dermatology · 2012
    6. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    7. De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle Journal of Investigative Dermatology · 2010
    8. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    9. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    10. The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009
    11. Cell Movement in the Hair Follicle Dermis: More Than a Two-Way Street? Journal of Investigative Dermatology · 2003
    12. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    13. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003

    Related research 8

    1. Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration British journal of dermatology/British journal of dermatology, Supplement · 2017
    2. Hair Follicle Regeneration In Vitro Paleontological Journal · 2016
    3. STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing Journal of Investigative Dermatology · 2016
    4. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    5. At the Dawn of Hair Research – Testing the Limits of Hair Follicle Regeneration Experimental Dermatology · 2014
    6. Application of Mesenchymal Stem Cells Derived from Bone Marrow and Umbilical Cord in Human Hair Multiplication Journal of dermatological science · 2010
    7. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    8. Optimization of the Reconstruction of Dermal Papilla-Like Tissues Employing Umbilical Cord Mesenchymal Stem Cells Biotechnology and bioprocess engineering · 2010