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The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

Gene differences may affect baldness treatment response in Korean men.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

KDML105 bran extract may help with hair growth and prevent hair loss.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

No link found between specific genes and female pattern hair loss.

HST and HST/F promote hair growth and may help treat alopecia.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

Bee venom helps hair grow and may work better than some common treatments.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.