1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
28 citations,
August 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Survivin protein is crucial for hair growth and preventing cell death in hair follicles.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking TYK2 might be a new way to treat hair loss from alopecia areata.
November 2022 in “Journal of Investigative Dermatology” The extract of Silybum marianum, Manganese PCA, and Lespedeza capitata can boost hair growth and extend the growth phase when combined in a serum.
March 2017 in “International journal of current advanced research” Medicated shampoos can help reduce hair loss associated with dandruff.
April 2016 in “Journal of Investigative Dermatology” SOX4 is crucial for the development of melanoma.
13 citations,
July 2015 in “Archives of dermatological research” N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.
11 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” New cell-based therapies may improve hair loss treatments in the future.
April 2019 in “Journal of Investigative Dermatology” The humanized AA mouse model is better for testing new alopecia areata treatments.
8 citations,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
15 citations,
December 2011 in “Journal of the European Academy of Dermatology and Venereology” Hair loss in systemic lupus erythematosus patients is unique and improves with treatment.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
59 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
5 citations,
January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
56 citations,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
33 citations,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
9 citations,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
5 citations,
May 2020 in “Pharmaceutical Research” Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
1 citations,
December 2015 in “Journal of the Medical Sciences (Berkala Ilmu Kedokteran)” Transplanting melanocyte stem cells from hair follicles can effectively treat vitiligo.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
2 citations,
August 2011 in “InTech eBooks” New methods for growing skin cells can improve skin grafts by building blood vessels within them.
63 citations,
September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
8 citations,
August 2016 in “Journal of pathology and translational medicine” CD99 is highly present in certain skin cells and could help treat skin conditions.
6 citations,
November 2010 in “Histochemistry and cell biology” The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
April 2021 in “Journal of Investigative Dermatology” The research found genes that may protect certain scalp cells from hair loss.
28 citations,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.