Cicatricial Alopecia: Overview and Treatment Options

    October 2018 in “ InTech eBooks
    Yingjun Su, Qing Yang, Wenjie Dou, Ping Xue, Xianjie Ma, Xianhui Zeng, Lei Wang, Chiyu Jia
    Image of study
    TLDR The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
    The document from October 31, 2018, provides an overview of cicatricial alopecia, a permanent hair loss condition due to the destruction of hair follicles and replacement with scar tissue. It distinguishes between primary cicatricial alopecia, which is an inflammatory condition targeting hair follicles, and secondary cicatricial alopecia, which results from nonspecific skin damage. Primary cicatricial alopecia is further classified based on the type of inflammatory cells involved. Treatments include immunosuppressive agents for lymphocyte-predominant lesions and antimicrobials or dapsone for neutrophil-predominant lesions, with autologous hair transplantation recommended for stable cases. The document notes a lack of consensus on treatment efficacy, with clinical improvement not fully supported by evidence-based trials. It also mentions that minoxidil may have antifibrotic effects in early stages of scarring alopecia, but its effectiveness varies among individuals. Hair transplantation techniques like FUE are considered for hair replacement, with outcomes depending on scalp preparation and post-surgery care. The document concludes that while various treatments have been attempted, their efficacy is not well-supported by evidence, and hair transplantation has shown more predictable and satisfactory results, though further research is needed.
    Discuss this study in the Community →

    Research cited in this study

    26 / 26 results

    Related Community Posts Join

    6 / 13 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Comprehensive Microneedling Guide

      in Microneedling  291 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

    Related Research

    3 / 3 results