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This study found that Plumbago zeylanica extract and its component plumbagin may help prevent androgenetic alopecia by promoting dermal papilla cell growth and reducing SRD5A2 expression.

This study synthesized nonsteroidal ligands as second-generation androgen receptor agonists and identified three compounds with significant anabolic activity and moderate to minimal androgenic activity in vivo.

Spironolactone helps prevent swelling caused by minoxidil in women with hair loss.

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

This review evaluates the anti-aging properties of TSG from He shou wu, finding it may protect against age-related diseases through multiple mechanisms, though further research is needed for clinical application.

This study suggests that silibinin enhances signaling pathways related to hair growth in three-dimensional cultured human dermal papilla cells, indicating its potential as a treatment for alopecia.

This study found that the extract of Bidens pilosa L. improved dry eye symptoms associated with androgen deficiency in rats by enhancing tear production, stabilizing the tear film, and reducing lacrimal gland inflammation.

This study found that a quinazoline derivative, SH-340, increased skin barrier-associated factors and inhibited TSLP expression and STAT6 phosphorylation in human primary keratinocytes, suggesting potential benefits for alleviating inflammation and improving skin barrier function in atopic dermatitis.

This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.

In this study, the researchers found that while the chitosan-alginate gel base supported hair growth, the addition of 0.5% celery extract did not enhance growth, likely due to its low concentration.

This study identified two cytochrome P450 enzymes in Avicennia marina leaves that may contribute to the biosynthesis of triterpenoids, potentially responsible for the plant's medicinal properties.

This study found that the ethanol extract of Sterculia urceolata and its fractions stimulated hair growth in male rabbits, with a 15% concentration of the water fraction showing the most significant effect.

This study found that Dendropanax, sea salt, spinach, and kelp were safe and potentially effective as ingredients in functional cosmetics aimed at alleviating hair loss symptoms.

Melatonin helps broccoli roots produce anti-cancer compounds by controlling nitric oxide and hydrogen peroxide levels.

In this paper, the authors detailed the role of 5-α-reductase in male androgenetic alopecia and discussed potential inhibitors like saw palmetto extracts, suggesting further investigation into their effects on hair follicles and associated biological processes.

In a testosterone-induced BPH rat model, this study found that ursolic acid treatment significantly reduced prostate weight and hormone levels, suggesting it may inhibit BPH development.

This study reported that compounds from the root of Beta vulgaris, specifically 4-picoline and Betalain, showed potential as effective anti-hair loss treatments by demonstrating significant inhibitory activity against the enzyme 5α-reductase in a computational molecular docking study.

This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.

This study found that transgenic safflower oil bodies expressing oleosin-rhFGF9 promoted significant hair regrowth and wound healing in mice compared to control groups.

This study found that LDE225, a novel Smo antagonist, shows potential as a topical treatment for basal cell carcinoma due to its high affinity binding and effective inhibition of tumor growth in preclinical models.

This study found that using a stevioside-based microneedle patch significantly increased minoxidil's solubility and skin absorption, promoting hair growth in animal models and achieving 67.5% area coverage by day 35, highlighting the potential of this novel delivery system for androgenetic alopecia treatment.

This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.

In this study, researchers addressed the limitations of adenosine's practical application in treating inflammation, oxidative stress, and tissue repair due to its poor water solubility and low transdermal permeability. Results are not reported in the abstract.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.

This study found that bisbenzylisoquinoline alkaloids from Stephania cepharantha Hayata stimulated growth in cultured murine hair cells but not in keratinocytes or fibroblasts.

This study found that in rats, finasteride significantly reduced allopregnanolone in the cortex and increased both the rise and duration of dopamine levels in the prefrontal cortex in response to stress and anxiogenic stimuli.

This study found that salinity stress in Arabidopsis thaliana root hairs may inhibit hair extension through changes in the tip-focused Ca(2+) gradient, while cytosolic pH remains unaffected.

In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.

This study demonstrated that aqueous and hydroethanolic extracts of Catharanthus roseus and Schwenckia americana showed no acute oral toxicity at the tested dose in rats, although histological changes in kidney and liver tissues were observed.