25 citations
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July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
20 citations
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September 2019 in “South African Journal of Botany” This study found that Teucrium polium L. subsp. geyrii Maire extract demonstrated a large safety margin in acute and subacute toxicity tests on mice and significantly enhanced wound healing in rats, especially with callus extract, by improving cell proliferation and wound contraction.
May 2026 in “Revista Ensaios Pioneiros” This study developed and evaluated topical formulations containing 5% minoxidil and 1% rosemary essential oil for androgenetic alopecia treatment, finding them physically and chemically suitable, but noted that further stability tests and clinical trials are needed to confirm therapeutic efficacy and safety.
June 2025 in “INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT” This study assessed a herbal dry shampoo comprising natural ingredients like Shikakai and Reetha, finding it effectively passed physicochemical tests but highlighted the need for more research to optimize product quality and safety.
4 citations
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February 2025 in “Pharmaceuticals” In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.
July 2024 in “Journal of Investigative Dermatology” ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
January 2024 in “Journal of Cosmetics Dermatological Sciences and Applications” This study investigated the safety and effectiveness of two thioglycolate chemical depilatory creams for full genital hair removal in men and women, finding acceptable dermal tolerance despite some instances of irritation, supporting their use for pubic hair grooming.
19 citations
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July 2019 in “Biomedical Microdevices” This review discusses the safety and potential adverse events of microneedling as both a medical and consumer product, noting the need for further understanding; no new clinical results are presented.
30 citations
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May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
November 2025 in “Journal of Pharmacognosy and Phytochemistry” This study aimed to formulate and test a hair conditioning mask using natural ingredients like flax seeds, rice water, and vitamin E, suggesting potential benefits in addressing issues like hair loss, dryness, frizziness, dullness, and dandruff while meeting customer demand for strong and shiny hair.
7 citations
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September 2024 in “Journal of Microbiology and Biotechnology” This study found that Peperomia pellucida, a plant traditionally consumed in some countries, contains various antioxidants and extends lifespan under oxidative stress in Drosophila, with no observed toxicity in mice, supporting its potential safety and use in foods and pharmaceuticals.
4 citations
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February 2019 in “Biological Trace Element Research” In this research, animal tests confirmed that chromium supplementation effectively maintains glycaemic and insulinaemic balance and affects certain hormone levels, but the authors note that clinical evidence for chromium's benefits in PCOS treatment remains sparse and inconsistent, warranting further exploration.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal hair oil formulated with medicinal plant-based ingredients, reporting its significant potential to promote hair growth, reduce hair fall and dandruff, and improve scalp health while maintaining stability and safety, suggesting it as a viable alternative to synthetic hair products.
49 citations
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December 2018 in “Asian Journal of Pharmaceutical and Clinical Research” This study formulated an herbal shampoo using various plant extracts and found it demonstrated appealing qualities, good foam stability, cleansing, and conditioning performance, though further improvements in quality and safety are needed.
11 citations
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January 2017 in “Evidence-based Complementary and Alternative Medicine” This study investigated the effects of the herbal formulation DA-5512 on hair growth, finding that it significantly promotes dermal papilla cell proliferation and stimulates hair growth in mice while showing efficacy and safety in human trials compared to placebo and minoxidil (3%).
2 citations
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August 2023 in “Journal of Natural Remedies” In this study, researchers developed a herbal anti-dandruff shampoo that demonstrated strong antifungal activity against Malassezia furfur and reported its conditioning performance to be comparable to market-available shampoos, though further research is needed to improve its quality and safety.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and evaluated an herbal hair dye using extracts from plants like henna and amla, which possess antibacterial and antioxidant properties, and found favorable results through various tests such as organoleptic and physico-chemical evaluations.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review summarizes current research on natural hair dyes, reporting that plant-based formulations can safely provide viable colors on gray hair with minimal irritation compared to synthetic options but face challenges in color range and consistency.
This study suggests that a herbal shampoo made from plant ingredients may be a promising natural remedy for hair fall and dandruff, demonstrating good quality and safety.
January 2023 in “Dermatologìâ ta venerologìâ” This study found that using a combination of "Volvit tablets" (biotin 5 mg) and "Volvit intensive care shampoo" with biotin in patients with diffuse telogen alopecia stopped hair loss and restored hair follicles to normal function, suggesting effectiveness and safety for wide clinical use.
15 citations
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December 2006 in “Clinical interventions in aging” This analysis of the Prostate Cancer Prevention Trial found that finasteride reduces prostate cancer risk by nearly 25% and enhances the PSA test's ability to detect prostate cancer and high-risk diseases.
7 citations
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January 2020 in “PubMed” In this review, researchers highlight preclinical and clinical studies on stem cell-based therapies for hair loss, noting promising early findings but indicating that further robust clinical research is necessary to better understand their effectiveness, safety, and mechanisms.
1 citations
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March 2023 in “Frontiers in Medicine” This meta-analysis found that topical prostaglandin analogs could significantly improve hair length and density in patients with hair loss, compared to placebo, without notable safety differences.
October 2024 in “Small Methods” This study found that dissolving microneedles loaded with platinum nanozymes induced faster hair growth in an androgenetic alopecia model than daily minoxidil applications, with no significant safety concerns.
29 citations
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April 2020 in “Biomolecules” This review discusses the potential biomedical and clinical applications of brassinosteroids, highlighting their observed antiviral, anticancerous, and other bioactivities in animal test systems, but reports no new findings.
13 citations
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November 2022 in “Biomaterials Science” This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.
7 citations
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October 2020 in “Dermatology practical & conceptual” This review discusses the potential risks associated with skin, hair, and nail supplements, highlighting concerns about safety, efficacy, and lack of regulation but reports no new clinical results.
4 citations
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March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” The study formulated a hair application Ayurvedic herbal oil using various plant materials, including Neem and Amla, and reported that all evaluated parameters, such as specific gravity and irritation tests, were acceptable and within standard limits.
2 citations
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January 2025 in “International Journal of Pharmaceutical Research and Applications” This study formulated an herbal shampoo using natural extracts and compared its physicochemical properties, such as pH and foam consistency, with commercial shampoos, finding that both performed similarly in conditioning tests conducted with twenty volunteers.