Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research

    April 2020 in “ Biomolecules
    Sukhmeen Kaur Kohli, Abhay Bhardwaj, Vinay Bhardwaj, Anket Sharma, Namarta Kalia, Marco Landi, Renu Bhardwaj
    TLDR Brassinosteroids may be useful in treating cancer, infections, and other diseases.
    Brassinosteroids (BRs), plant-derived steroids, were found to have significant therapeutic potential in biomedical and clinical research due to their diverse biological activities. They exhibited antiviral, anticancer, anti-inflammatory, antifungal, and antibacterial properties. BRs inhibited virus replication, induced cytotoxic effects on cancerous cell lines, and modulated the cell cycle. They also enhanced plant resistance against viruses and infections, demonstrated antiangiogenic properties, and showed promise in reducing inflammation and cholesterol levels. The research suggested that BRs could be developed into new therapeutic agents for conditions like cancer, viral infections, and metabolic disorders, highlighting their broad applications and safety profile.
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