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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

MED1 affects skin wound healing differently in young and old mice.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Vitamin D3 may protect rat hair follicles from radiation damage.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Thyroid problems are linked to various skin issues, and checking thyroid health is important for people with certain skin conditions.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Topical retinoids effectively improve photodamaged skin.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.