Acne Vulgaris
March 2017
in “
InTech eBooks
”
acne vulgaris keratinization P. acnes hormonal influences sebum production inflammatory mediators genetic factors immune system interactions high glycemic-load diets dairy topical retinoids benzoyl peroxide oral antibiotics hormonal therapies isotretinoin combination therapies surgical options Propionibacterium acnes Accutane
TLDR Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
The document reviewed Acne vulgaris, a common skin condition affecting 40-50 million individuals annually in the USA, particularly 85% of young people between 12 and 24 years of age. It detailed the psychosocial impact, including low self-esteem and depression, with up to 21% of acne patients experiencing body dysmorphic disorder. The pathogenesis involves altered keratinization, P. acnes activity, hormonal influences, sebum production, and inflammatory mediators, with genetic factors and immune system interactions also playing roles. Dietary factors like high glycemic-load diets and dairy may exacerbate acne, which presents clinically with various lesion types. Early treatment is crucial to prevent scarring. Treatment options include topical retinoids, benzoyl peroxide, oral antibiotics, hormonal therapies, and isotretinoin, with the latter being the choice for severe cases but having potential side effects and contraindications. Combination therapies are recommended for optimal outcomes, and surgical options are available for severe cases and scarring.
