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Skin Expression of Mammalian Target of Rapamycin and Forkhead Box Transcription Factor O1, and Serum Insulin-Like Growth Factor-1 in Patients with Acne Vulgaris and Their Relationship with Diet

research Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet

93 citations , January 2016 in “British Journal of Dermatology”

This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.

research Acne: Diet and acnegenesis

11 citations , January 2011 in “Indian Dermatology Online Journal”

This article discusses a proposed molecular mechanism linking dietary factors to acne but reports no new clinical findings.

research Role of insulin resistance and diet in acne

39 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This article discusses the role of growth hormone, insulin, and IGF-1 in acne development and highlights how diet and syndromic evidence support their involvement, but presents no new clinical findings.

research A Comprehensive Review of Acne Vulgaris

18 citations , June 2019 in “Clinical research in dermatology”

This review discusses psychological impacts associated with facial acne, noting that high levels of anxiety and depression among these patients are not linked to oxidative stress, and reports no new clinical results.

research Acne Vulgaris

March 2017 in “InTech eBooks”

This source provides a comprehensive review of acne vulgaris, highlighting its pathophysiology, epidemiology, molecular mechanisms, and treatment options, emphasizing the significance of addressing acne's psychosocial burden for adolescents and beyond.

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community Sugar and Hair loss connections

in Research/Science 41 upvotes 1 year ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community 1.5 years on 1.2 Mg fin. Minimal results. Recently switched to dutasteride.

in Finasteride/Dutasteride 23 upvotes 4 months ago

The user has been on 1.2 mg finasteride for 1.5 years with minimal results and recently switched to dutasteride. Suggestions include adding minoxidil, derma rolling, and considering dietary changes to improve hair health.

community A FULL YEAR of progress! (min & fin) GETTING WORSE!

25 upvotes 4 months ago

A 21-year-old's hair loss worsened despite using finasteride, oral and topical minoxidil, microneedling, and keto shampoo for a year. They are considering switching to dutasteride and improving their diet.

community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 4 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001).

297 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

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