Facial Hypertrichosis After Isotretinoin Therapy: Is It a Side Effect or Coincidence?

    March 2022 in “ Turkderm ”
    Esra Saraç, Alkım Ünal
    Image of study
    TLDR Isotretinoin may cause temporary, reversible facial hair growth in some women.
    The study investigated the occurrence of facial hypertrichosis in 30 premenopausal female patients with acne vulgaris during and after isotretinoin treatment. With a mean therapy duration of 6.2±0.6 months, facial hair growth was observed in 10% of the patients, although it resolved spontaneously within 1-3 months post-treatment. The study suggests that isotretinoin may cause temporary hormonal imbalances leading to hair growth in susceptible individuals, but acknowledges that the exact mechanism is unclear. Despite the small sample size and lack of a control group, the findings indicate that the hypertrichosis side effect is reversible and further research is needed to understand the drug's impact on hair growth. The study recommends endocrinological and psychological assessments for patients undergoing isotretinoin therapy.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 816 results

      community Oral minoxidil can causes age skin?

      in Minoxidil  8 upvotes 2 years ago
      Oral minoxidil may cause skin aging, such as dark circles. To counteract aging, use tretinoin at night and broad-spectrum sunscreen during the day.

      community Oral Minoxidil Users In A Nutshell

      in Satire  1218 upvotes 3 years ago
      This conversation is about hair loss treatments, specifically oral minoxidil and finasteride. Users discussed the potential side effects of using these drugs, as well as their experiences with them.

      community POV: You Ask A Tressless User If It's Safe To Drink Minoxidil

      in Satire  769 upvotes 3 years ago
      This conversation is about how topical treatments for hair loss, such as Minoxidil and Finasteride, can be replaced by drinking oral versions of the same medications to achieve better results with less hassle. Some users have already been doing this with positive results.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 2 weeks ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

    Similar Research

    5 / 1000+ results