13 citations
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March 2017 in “Genomics” This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.
13 citations
,
November 2014 in “Clinics in Plastic Surgery” This article reviews the use of the transtemporal approach for midface and lower eyelid-cheek junction rejuvenation, detailing surgical techniques, post-operative care, and potential complications, but reports no new clinical results.
12 citations
,
September 2020 in “Journal of cosmetic dermatology” This study found that trichoscopy aided in assessing treatment responses for patchy alopecia areata, with both intralesional corticosteroids and platelet-rich plasma showing effectiveness, but only PRP significantly improved patient symptom impact scores.
12 citations
,
January 2013 in “IOSR Journal of Agriculture and Veterinary Science” In this study, homogenous platelet rich plasma gel improved wound healing in goats, showing organized collagen and new hair growth within 15 days without inflammation.
11 citations
,
May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
11 citations
,
August 2020 in “Diabetes” This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.
11 citations
,
June 2020 in “Journal of cosmetic dermatology” In this study, a home-use microneedle device combined with 5% minoxidil showed potential for enhancing hair growth in pattern hair loss over six months, although the observed improvements in hair count and patient assessments were not statistically significant compared to other treatments.
11 citations
,
June 2020 in “Dermatologic Therapy” This study suggests that combination therapies including minoxidil with either finasteride, low-level laser light therapy, or microneedling are more effective than minoxidil alone for treating androgenetic alopecia.
11 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This commentary reviews the evidence for microinflammation's role in pattern hair loss and suggests that further studies with age- and sex-matched controls are needed to substantiate the findings.
11 citations
,
March 2020 in “Cellular Signalling” In this study, knockdown of XIST in 3D-cultured dermal papilla cells inhibited hair follicle regeneration by interfering with miR-424 and hedgehog signaling, highlighting XIST's role in hair development.
11 citations
,
March 2020 in “American Journal of Medical Genetics Part A” This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.
11 citations
,
December 2019 in “Dermatologic Therapy” This systematic review suggests that topical ketoconazole may improve hair regrowth and thickness in both animal and human studies for androgenetic alopecia, but further randomized controlled trials are needed.
11 citations
,
November 2009 in “Sports Medicine” This review explores whether oligomenorrhoea in exercising women is a mild subclinical phenotype of PCOS or part of a spectrum of energy deficiency-related menstrual disturbances, without new clinical results.
10 citations
,
September 2020 in “Journal of Cosmetic Dermatology” In this study, microneedling with a depth of 0.6 mm, alongside minoxidil, significantly improved hair count and thickness in patients with androgenetic alopecia compared to minoxidil alone, and was more beneficial than a 1.2 mm depth.
10 citations
,
June 2020 in “Journal of Cosmetic Dermatology” This study found a high prevalence of genital Lichen sclerosus and autoimmune comorbidities in patients with frontal fibrosing alopecia, suggesting a possible shared autoimmune process.
10 citations
,
May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
10 citations
,
January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
10 citations
,
January 2018 in “Organogenesis” This study found that epidermal stem cell-specific Jag1 expression levels are crucial for effective wound healing and scar reduction, and porcine acellular dermal matrix treatment enhances this process in mice by boosting Notch/Jagged1 signaling.
10 citations
,
November 2014 in “Journal of Dermatological Treatment” This review examines clinical trials on polyphenol-based therapies for dermatological conditions, suggesting potential benefits for anogenital warts, alopecia, and acne, but calls for more rigorous trials.
9 citations
,
May 2020 in “Journal of Cosmetic Dermatology” This review discusses various follicular unit excision methods, punch designs, and motorized devices, highlighting their roles in reducing hair follicle transection rates and optimizing graft harvesting for individual patient characteristics.
9 citations
,
August 2019 in “Clinical genitourinary cancer” This study suggests that 5-alpha reductase inhibitors may reduce invasive cancer features and improve survival in men undergoing radical cystectomy for high-grade urothelial carcinoma, although further research is needed to confirm these findings.
9 citations
,
January 1995 in “Aesthetic Plastic Surgery” This study observed that using a relaxed suture technique on scalp incisions may prevent linear scars by reducing pressure on upper stem cells.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” This review discusses the roles of adiponectin and bradykinin in skin homeostasis and pathologies, highlighting the need for further research into their therapeutic potential but reports no new clinical results.
8 citations
,
September 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that women, younger individuals, and those with a low body mass index were more likely to develop long COVID symptoms, and even mild COVID-19 cases often experienced long-term residual symptoms.
8 citations
,
June 2021 in “Journal of Cosmetic Dermatology” This review details various skin manifestations linked to COVID-19 and highlights dermatitides caused by personal protective equipment, emphasizing the need for accurate diagnosis and prompt treatment.
8 citations
,
July 2020 in “International Journal of Pharmaceutics” In this study, complexation with cyclodextrins was reported to increase the solubility of FIN for potential use in aqueous formulations for treating male androgenic alopecia.
8 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This study found that androgenetic alopecia is a significant yet under-recognized cause of hair loss in children and adolescents, often linked to family history and typically diagnosed by clinical examination.
8 citations
,
December 2018 in “Journal of Dermatological Treatment” This study found that a PRP-like cosmetic product called TR-M-PRP plus significantly improved hair growth in individuals with alopecia areata over three months, as measured by the SALT score, suggesting it could be a safer alternative to traditional PRP treatments.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” This study suggests that in gilthead seabream, DHT is involved in the onset of the meiotic phase of spermatogenesis and influences serum levels of E2 through regulation of aromatase activity.
8 citations
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July 2017 in “Biochemical and biophysical research communications” This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.