January 2020 in “Asian Journal of Chemistry” This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.
90 citations
,
November 2014 in “Journal of Biomedical Optics” In this study, silver nanoparticles were found to penetrate porcine skin to depths ranging from 11.1 μm to 15.6 μm, potentially surpassing the stratum corneum thickness.
January 2023 in “SSRN Electronic Journal” This study found that a fibroin-based cosmetic ingredient improved the mechanical properties and cuticle repair of African-American and Caucasian hair types, even when damaged by chemical treatments.
13 citations
,
January 2017 in “Cosmetics” This review discusses in vitro methods for evaluating the effects of hair care products on hair fibers, reporting no new results; the authors emphasize the importance of selecting appropriate and accurate equipment for testing.
October 2024 in “Cosmetics” In this study, reducing agents like ammonium thioglycolate, L-cysteine, and sodium sulfite in shampoo effectively decreased hair flyaway and frizz without causing damage, as no critical hair damage was observed in structural and tensile strength assessments.
6 citations
,
January 2024 in “ACS Medicinal Chemistry Letters” This study found that the alkaloids cepharanthine and berbamine bind to SK2 and SK3 channel subtypes with affinities that match their concentrations active against various diseases, prompting further investigation into SK channels' role in their therapeutic effects.
70 citations
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June 1998 in “Polymer” This study found that permanent waving treatment partially disrupts the α-helical structure in human hair microfibrils, primarily during the initial reduction phase, rather than just affecting disulphide bonds.
5 citations
,
July 2021 in “Endocrinology, diabetes & metabolism” This study found that glioblastoma cells express key enzymes involved in androgen synthesis, suggesting these enzymes might be potential targets for new therapeutic strategies.
6 citations
,
July 2007 in “Organic Process Research & Development” This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.
July 2016 in “American Journal of Dermatopathology” The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.
17 citations
,
November 2024 in “Talanta” A new method was developed to detect pesticide residues on apples without damage.
15 citations
,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identifies KLK14 as a significant factor contributing to hair defects and skin inflammation in a mouse model of Netherton syndrome.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.
1 citations
,
December 2016 in “Revista română de medicină de laborator” This study reported the first case of a NIPAL4 c.527C>A mutation in Romanian patients with autosomal recessive congenital ichthyosis, finding that NIPAL4 mutations are more common than TGM1 mutations in this population.
2 citations
,
December 2023 in “Journal of clinical immunology” This study describes the positive effects of the JAK inhibitor ruxolitinib in treating autoimmune manifestations in three patients with autoimmune polyendocrine syndrome type-1 over a period of at least 30 months, with excellent tolerance and no adverse events observed.
5 citations
,
January 2022 in “Journal of Cosmetic Dermatology” This review summarizes documented cases of hair and ungual changes associated with COVID-19, which may help to further understand the disease's clinical implications.
130 citations
,
November 2017 in “Frontiers in Immunology” This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
25 citations
,
December 2008 in “The Journal of Urology” In this study, short-term finasteride treatment reduced apoptotic factors caspase-7 and IGFBP-3 in prostate cancer cells but did not significantly affect androgen receptor expression compared to placebo.
December 2025 in “The Journal of Cell Biology” This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.
February 2024 in “International journal of molecular sciences” This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.
36 citations
,
September 2019 in “Journal of Herbal Medicine” This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
December 2024 in “Archives of Clinical & Experimental Dermatology” This controlled study found that patients with androgenetic alopecia treated with a combination of subcutaneous adipose-derived mesenchymal stem cells and oral minoxidil showed significantly better hair growth outcomes than those treated with oral minoxidil alone, with improvements ranging from 25-40% versus 5-10% over six months.
271 citations
,
September 2008 in “Nutrition reviews” This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.
555 citations
,
April 2002 in “The Lancet” This study found that off-pump coronary surgery significantly reduces in-hospital morbidity compared to on-pump surgery without affecting midterm outcomes in the first 1-3 years after the procedure.
4 citations
,
April 2022 in “Animals” This study found that environmental conditions significantly influenced rabbit coat quality, while dietary linseed oil supplementation changed the fatty acid profile but did not improve coat thickness or heat protection.
24 citations
,
December 2016 in “Stem Cell Research & Therapy” This study found that P311 triggers transdifferentiation of epidermal stem cells into myofibroblast-like cells via TGFβ1/Smad signaling during wound healing.
2 citations
,
December 2024 in “Iraqi Journal of Laser” This study used enhanced Raman spectroscopy to successfully detect ultra-low levels of free testosterone in women with PCOS, suggesting a potential low-cost method for early diagnosis.
26 citations
,
October 2016 in “Biomolecules & Therapeutics” This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.
11 citations
,
November 2021 in “International journal of molecular sciences” In this study, germ-free male mice showed altered levels of certain neuroactive steroids in the brain and periphery, suggesting microbiota may influence neuroendocrine pathways that support brain functioning.
This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.