Identification and Detection of Finasteride Polymorphs in Finasteride Tablets by FT-Raman Spectroscopy

    January 2020 in “ Asian Journal of Chemistry ”
    M. S. Ramachandra Rao, R. Ramakrishna Reddy, K.B. Chandra Sekhar, Y.C. Janardhan Reddy
    TLDR Raman spectroscopy can identify finasteride polymorphs in tablets.
    The study developed a simple FT-Raman spectroscopic method to identify finasteride polymorphs in tablets, specifically detecting polymorph form I used in tablet preparation, which constituted about 2.3% of the tablet's weight. The method successfully identified the polymorphic form and detected up to 15% of another polymorph in the solid dosage. Various techniques, including powdered X-ray diffraction, infrared spectroscopy, and Raman spectroscopy, were used to characterize the dosage form, with Raman spectroscopy being the only method capable of identifying the polymorph in the dosage form.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Why does it seem everyone favors finasteride over dutasteride?

      in Female  62 upvotes 7 months ago
      The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

      community Maintaining hair until Breezula without Fin

      in Treatment  6 upvotes 4 years ago
      A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

      community Dutasteride Literally Saves Your Hair

      in Finasteride/Dutasteride  96 upvotes 6 months ago
      Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

      community 8-9 Month Update. 24M Korean Diffuse Thinner

      in Progress Pictures  311 upvotes 11 months ago
      The conversation discusses a 24-year-old Korean man's progress with hair loss treatments over 8-9 months, with specific treatments not mentioned due to redacted information. Users are commenting on the effectiveness and inquiring if Asians have better results with hair loss treatments.

      community Topical fin formulation question

      in Finasteride  91 upvotes 1 week ago
      A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.

      community Topical finasteride carrier/vehicle

      in Finasteride  135 upvotes 3 weeks ago
      The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

    Similar Research

    5 / 1000+ results