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Targeting the Smoothened receptor shows promise for treating certain cancers.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Human stem cells can help form hair follicles in mice.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Baricitinib reduces inflammation and improves cell health in premature aging cells.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

Akebia quinata and Akebia trifoliata have many health benefits and potential medical uses.

Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.

VDR regulation varies by tissue and is crucial for its biological functions.

Tailored treatments for alopecia areata are recommended based on severity and patient needs.

Mushroom beta-glucans from Ganoderma lucidum can reduce tumor size and metastasis in cancer.

Keratin from hair binds well to gold and BMP-2, useful for bone repair.

The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.

Different species use the same genes for tooth regeneration.

Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Old hair follicles grew better when moved to a young environment.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Omega-6 fats in certain cells boost male hormone production.

Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Transplanted hair follicle stem cells can heal damaged rat intestines.

Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.