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This study introduces Cell Journey, a new platform for visualizing RNA velocity in 3D, which aims to better capture complex cellular transitions in single-cell datasets compared to current 2D methods.

In this study of four Chinese goat breeds, black goats exhibited significantly higher melanin content, while Inner Mongolian cashmere goats had longer fiber lengths. These findings highlight genetic variations in coat color and fiber length, informing future breeding programs.

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.

This study found that photoexposure significantly increased the gene expression of altered elastin, MMP12, and LOX, as well as the protein expression of tropoelastin and fibrillin-1, in skin models.

This study found that nasal swab DNA collection was more convenient and yielded higher quality and quantity DNA samples than blood collection in both Angus cattle and yaks.

This study documented distinct expression patterns of stem cell markers LGR5 and LGR6 in various human skin tumors, highlighting differences in their potential roles and contributions to tumor development.

This study identified differentially expressed miRNAs between the telogen and anagen phases of hair growth in Wan Strain Angora rabbits, contributing to understanding miRNA-mediated regulation of rabbit hair follicle cycling.

In this study, researchers developed a simplified and reliable method to prepare human hair shaft samples, achieving over 75% protein extraction efficiency and improved keratin sequence coverage, with the approach showing high reproducibility across different labs and operators.

This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.

In this study, researchers identified a collagen fragment, sample-1707, expressed in E. coli, which forms nanofibers and promotes blood clotting, osteoblast differentiation, and skin cell regeneration, making it a promising biomaterial for skin care, with a large-scale production yield of 600 mg/L.

This study used proteomic profiling to reveal significant individual and site-specific differences in human hair shaft proteins, which may improve the differentiation of hair based on ethnic origin and individual identity.

This study identified five master regulators that mediate molecular differences in hair follicle development and sexual dimorphism in the skin, providing insights into male pattern baldness and hair follicle donor dominance.

This systematic review found that topical adenosine may increase hair thickness and density while reducing hair loss, but the strength of evidence is low due to issues with trial design and sample size.

In this study, deep learning models accurately predicted gene expression in whole slide images of colorectal cancer, with convolutional neural networks outperforming transformer and graph-based approaches in spatial RNA pattern prediction.

This study identified distinct gene expression patterns in wool follicle bulbs that may play important roles in wool follicle cycling and regeneration in sheep.

This study indicates that sheep prenatally androgenized with testosterone show wool fiber diameter changes that parallel the increased hair diameter in women with polycystic ovary syndrome.

This study identified key genes and signaling pathways involved in cashmere goat hair follicle growth cycles, influenced by melatonin implantation, suggesting a basis for further research on melatonin's regulatory mechanism.

In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.

In this experimental study, laser irradiation significantly altered the gene expression of cytokines in cultured human T-cell lymphocytes, suggesting that such laser light may photobiomodulate cytokine production in vitro.

This study suggests that the expression of the DP2 receptor is higher in balding scalp cells and that its knockdown could inhibit the transition to the catagen phase in cultured human hair follicles, potentially counteracting hair growth inhibition associated with male pattern baldness.

This study suggests that targeting the increased expression of SIX1 in systemic sclerosis may be a viable strategy for addressing dermal fibrosis.

This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.

This study found high levels of toxic heavy metals in water sources of mining communities in Abakaliki, Nigeria, posing potential health risks including Parkinson's and Alzheimer's diseases.

This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.

This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.

This study found that self-noncoding dsRNA activates TLR3 to stimulate intrinsic retinoic acid synthesis, promoting new hair follicle formation in wounded mice and showing similar gene expression changes in humans treated with rejuvenation lasers.

This study found that basal cell carcinomas show strong expression of vitamin D receptors at both mRNA and protein levels, suggesting a potential role in tumor growth regulation.

This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.

This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.