Integrative Skin Phenotypic and Transcriptomic Analyses Reveal Candidate Genes for Coat Color and Fiber Length in Four Chinese Goat Breeds (Capra hircus)

    January 2026 in “ Animal Advances ”
    Min Xiao, Yingjie Wu, Yanli Lv … Yongju Zhao
    Studysummary In this study of four Chinese goat breeds, black goats exhibited significantly higher melanin content, while Inner Mongolian cashmere goats had longer fiber lengths. These findings highlight genetic variations in coat color and fiber length, informing future breeding programs.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on maxapress.com →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Whole-Transcriptome RNA Sequencing Reveals Global Expression Dynamics and ceRNA Regulatory Networks Related to Hair Follicle Development and Melanogenesis in Goats Animal Bioscience · 2025
    2. Phenotypic, Transcriptomic, and Genomic Analyses Reveal the Spatiotemporal Patterns and Associated Genes of Coarse Hair Density in Goats 动物学研究 · 2025
    3. Deletions in the KAP6-1 Gene Are Associated with Fiber Traits in Cashmere-Producing Goats Animal biotechnology · 2021
    4. Generation of VEGF Knock-In Cashmere Goat via the CRISPR/Cas9 System International Journal of Biological Sciences · 2021
    5. Mammalian-Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Nails and Hair Follicles Proceedings of the National Academy of Sciences · 2020
    6. Transcriptome-Based Selection and Validation of Optimal Housekeeping Genes for Skin Research in Goats (Capra Hircus) BMC Genomics · 2020
    7. Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing International Journal of Biological Sciences · 2018
    8. Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat Genetica · 2017
    9. Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers PLoS ONE · 2016
    10. Comparative Transcriptome Analysis Reveals That a Ubiquitin-Mediated Proteolysis Pathway Is Important for Primary and Secondary Hair Follicle Development in Cashmere Goats PLoS ONE · 2016
    11. XEDAR Activates the Non-Canonical NF-κB Pathway Biochemical and Biophysical Research Communications · 2015
    12. Fundamental Hair Follicle Biology and Fine Fibre Production in Animals animal · 2010
    13. Edar Signaling in the Control of Hair Follicle Development ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    14. Hox in Hair Growth and Development Die Naturwissenschaften · 2003