Deletions in the KAP6-1 Gene Are Associated with Fiber Traits in Cashmere-Producing Goats

February 2021 in “ Animal biotechnology ”

Jin Zhao, Qiang Ding, Lan Li, Peter Kalds, Shiwei Zhou, Jiayuan Sun, Shuhong Huang, Xiaolong Wang, Yulin Chen

KAP6-1 gene fiber traits cashmere-producing goats fiber diameter fiber length selective breeding genetic insight

TLDR Certain changes in the KAP6-1 gene affect the thickness and length of cashmere goat fibers.

The study investigated the association between deletions in the KAP6-1 gene and fiber traits in cashmere-producing goats. The findings suggested that specific deletions in the KAP6-1 gene were significantly correlated with variations in fiber diameter and length, which are critical traits for cashmere quality. This genetic insight could potentially be used to improve selective breeding programs aimed at enhancing cashmere fiber characteristics.

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Research cited in this study

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Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

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The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

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KAP genes show significant genetic variability, but its impact on hair traits is unclear.

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Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

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100 citations, December 2002 in “Journal of biological chemistry/The Journal of biological chemistry”

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

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48 citations, November 2002 in “Journal of biological chemistry/The Journal of biological chemistry”

Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.

Related Research

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research Deletions in the KAP6-1 Gene Are Associated with Fiber Traits in Cashmere-Producing Goats

1 citations, February 2021 in “Animal biotechnology”

Certain changes in the KAP6-1 gene affect the thickness and length of cashmere goat fibers.

research Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family

27 citations, June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.