Bidirectional Binding Property of High Glycine–Tyrosine Keratin-Associated Protein Contributes to the Mechanical Strength and Shape of Hair

    June 2013 in “ Journal of structural biology ”
    Ryo Matsunaga, Ryota Abe, Daisuke Ishii … Kouhei Tsumoto
    Studysummary This study suggests that the mechanical robustness of hair may be enhanced by the binding interactions of keratin-associated proteins, particularly KAP8.1, with intermediate filament proteins.
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    Research cited in this study 17

    1. Characterization of the Human Hair Keratin-Associated Protein 2 (KRTAP2) Gene Family Journal of Investigative Dermatology · 2012
    2. An Updated Nomenclature for Keratin-Associated Proteins International Journal of Biological Sciences · 2012
    3. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    4. Novel Type I Hair Keratins K39 And K40 Are The Last To Be Expressed In Differentiation Of The Hair: Completion Of The Human Hair Keratin Catalog Journal of Investigative Dermatology · 2007
    5. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    6. Human Hair Keratin-Associated Proteins International review of cytology · 2006
    7. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    8. Nucleation and Growth of Macrofibrils in Trichocyte (Hard-Alpha) Keratins Journal of Structural Biology · 2003
    9. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    10. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    11. In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments ˜The œjournal of cell biology/˜The œJournal of cell biology · 2000
    12. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    13. Ultrastructural Visualization of Cross-Linked Protein Features in Epidermal Appendages Journal of Cell Science · 1994
    14. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    15. Structure and Biochemistry of Mammalian Hard Keratin Electron Microscopy Reviews · 1991
    16. The Cytology and Cytochemistry of the Wool Follicle International review of cytology · 1979
    17. Iε-(γ-Glutamyl) Lysine Cross-Linkage in Citrulline-Containing Protein Fractions From Hair Biochemistry · 1971