research The Role of Nrf2 in Hearing Loss
Activating Nrf2 can help protect against hearing loss.
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research Skin
Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.
research Gamma-Aminobutyric Acid Promotes the Inhibition of Hair Growth Induced by Chronic Restraint Stress
GABA contributes to stress-related hair loss, and ginkgolide A may help treat it.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR-Cas9 in the Genetic Improvement of Sheep and Goats
CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.
research Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in Non-Mendelian Inheritance-Mediated Feather Growth Rate in Chickens
The research found specific genes and proteins that affect how fast chickens' feathers grow, which is not solely determined by traditional inheritance patterns.
research Medical Therapies
Combination therapies might work better for some vitiligo patients, but results vary.
research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
research DKK1-Targeting Cholesterol-Modified siRNA Implication in Hair Growth Regulation
Blocking DKK1 with siRNA can improve hair growth.
research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Chronic Inflammatory Diseases Stimulated by Current Lifestyle: How Diet, Stress Levels, and Medication Prevent Our Body from Recovering
Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research Crosstalk Between Endothelial Cells and Dermal Papilla Entails Hair Regeneration and Angiogenesis During Aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
research Identification of Potential Biomarkers for Diagnosis of Patients with Methamphetamine Use Disorder
Gene expression in hair follicles can help diagnose methamphetamine use disorder.
research Traditional Chinese Medicine Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Autofluorescence as a Signal to Sort Developing Glandular Trichomes by Flow Cytometry
Autofluorescence can sort plant cells without labeling.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research AP Collagen Peptides (APCPs) Promote Hair Growth by Activating the GSK-3β/β-Catenin Pathway and Improve Hair Condition
AP collagen peptides help hair grow and improve hair health.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Schmallenberg Virus Infection Suspected in a Calf Born to an Imported Heifer
A calf in Scotland likely had Schmallenberg virus from its mother.
research Bioengineered Polyester Nanoparticles for the Synergistic Treatment of Androgenic Alopecia via the Suppression of 5α-Reductase and Knockdown of Androgen Receptor
Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Disruption of Tubular Flcn Expression as a Mouse Model for Renal Tumor Induction
Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
research Catalytic Antibodies in Normal and Systemic Lupus Erythematosus
Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea
Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
research Construction of the Coexpression Network Involved in the Pathogenesis of Thyroid Eye Disease via Bioinformatics Analysis
Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.