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Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Aminoacridine and Abemaciclib, especially combined with Minoxidil, show promise for treating hair loss.

Adding a second method to PROTACs could improve cancer treatment.

Long-term high-dose fluconazole can cause reversible hair loss.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

As of December 2021, the most effective COVID-19 treatments were monoclonal antibodies and possibly early-administered convalescent plasma, while several drugs were found ineffective or were still under evaluation.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Eliminating senescent cells can prevent and reverse chemotherapy-induced peripheral neuropathy.

Researchers found three different ways drugs work to treat hair loss from alopecia areata and identified key factors for personalized treatment.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Frontal Fibrosing Alopecia involves disrupted cholesterol pathways, fibrosis, and increased mast cells.

Minoxidil may help reduce aging effects in brain cells.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

Finasteride helps female-pattern hair loss.

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

A blood pressure drug, diltiazem, may also help treat influenza.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.

Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Women with hair loss have more androgen receptors in certain hair follicles.

The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

Researchers improved a method to study individual cells in newborn mouse skin and found a way to assess the severity of a skin condition in humans.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Porphyra-334 may help reduce wrinkles and promote hair growth.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.