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GlossaryReverse Transcription Polymerase Chain Reaction

method to convert RNA into DNA and amplify it

Reverse Transcription Polymerase Chain Reaction (RT-PCR) is a laboratory technique used to convert RNA into DNA and then amplify specific DNA sequences. This method is crucial for studying gene expression, detecting RNA viruses, and diagnosing diseases, as it allows scientists to measure the amount of RNA in a sample by first transcribing it into complementary DNA (cDNA) and then amplifying it for analysis.

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Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in Non-Mendelian Inheritance-Mediated Feather Growth Rate in Chickens

research Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in Non-Mendelian Inheritance-Mediated Feather Growth Rate in Chickens

January 2024 in “Biochemical genetics”

The research found specific genes and proteins that affect how fast chickens' feathers grow, which is not solely determined by traditional inheritance patterns.

research Effects of Natural Herbal Marker Compounds on Human Dermal Papilla Cell Growth Regulation

December 2023

Four natural compounds were found to promote hair growth effectively.

research Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats

14 citations, June 2020 in “BMC genomics”

The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.

Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss Side Effect

research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss Side Effect

15 citations, February 2019 in “Journal of clinical medicine”

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

research Clinical Picture, Diagnosis, Treatment, and Outcome of Severe Acute Respiratory Syndrome (SARS) in Children

42 citations, November 2004 in “Paediatric Respiratory Reviews”

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

research Characterization and Expression Analysis of KAP7.1 and KAP8.2 Genes in Liaoning New-Breeding Cashmere Goat Hair Follicles

48 citations, February 2010 in “Molecular biology reports”

KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.

research Skin-Specific Transgenic Overexpression of Ovine β-Catenin in Mice

2 citations, January 2023 in “Frontiers in Genetics”

Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.

research Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer

December 2023 in “Animals”

The research found genes and miRNAs that may control hair growth in Forest Musk Deer.

research The Effect of JAK Inhibitor on Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells

16 citations, July 2020 in “International Journal of Molecular Sciences”

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

research SlPHL1, a MYB-CC Transcription Factor Identified from Tomato, Positively Regulates the Phosphate Starvation Response

11 citations, July 2021 in “Physiologia Plantarum”

SIPHL1 from tomato enhances plants' response to low phosphate levels.

research Genomewide Differential Expression Profiling of Long Non-Coding RNAs in Androgenetic Alopecia in a Chinese Male Population

11 citations, April 2017 in “Journal of The European Academy of Dermatology and Venereology”

Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.

research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects

September 2021 in “Research Square (Research Square)”

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes

5 citations, October 2020 in “Frontiers in Cell and Developmental Biology”

Reducing FOXA2 in skin cells lowers their ability to grow hair.

research Expression of Lipid-Protein Gene PLP2 in Liaoning Cashmere Goat

3 citations, February 2019 in “Animal biotechnology”

The PLP2 gene affects cashmere fiber quality in goats and is linked to hair growth and loss.

research Detection of Hair MicroRNAs as Novel Potent Biomarkers: Evaluation of Usefulness for Scleroderma Diagnosis

39 citations, July 2013 in “Journal of dermatological science”

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

research Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation

67 citations, December 2008 in “Developmental Biology”

Msx2 and Foxn1 are both crucial for hair growth and health.

research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth

10 citations, May 2012 in “PloS one”

Low ERCC3 gene activity is linked to non-pigmented hair growth.

research CC-Type Glutaredoxins Mediate Plant Response and Signaling Under Nitrate Starvation in Arabidopsis

36 citations, November 2018 in “BMC plant biology”

ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.

research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion

34 citations, July 2009 in “Journal of Cell Science”

ΔNp63α helps control a protein that stops cancer cells from spreading.

research Abstracts

October 2020 in “Veterinary Dermatology”

New treatments and diagnostic methods for various animal skin conditions showed promising results.

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

9 citations, May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.

Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

4 citations, July 2020 in “Biochemical and Biophysical Research Communications”

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

research Pharmacological Evidence for the Involvement of Adenosine Triphosphate Sensitive Potassium Channels in Chloroquine-Induced Itch in Mice

9 citations, June 2017 in “Pharmacological Reports”

ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.

research Generation of iPS Cells from Human Hair Follicle Dermal Papilla Cells

8 citations, January 2014 in “PubMed”

Researchers made stem cells from human hair follicle cells with better efficiency than from skin cells.

Reshaped DNA Methylation Cooperating with Homoeolog-Divergent Expression Promotes Improved Root Traits in Synthesized Tetraploid Wheat

research Reshaped DNA Methylation Cooperating with Homoeolog-Divergent Expression Promotes Improved Root Traits in Synthesized Tetraploid Wheat

February 2024 in “New phytologist”

DNA changes in tetraploid wheat improve root growth and nitrogen use.

research Induced Pluripotent Stem Cells From Human Hair Follicle Keratinocytes As A Potential Source For In Vitro Hair Follicle Cloning

18 citations, November 2016 in “PeerJ”

Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.