research Stability of Polylactic Acid Particles and Release of Fluorochromes Upon Topical Application on Human Skin Explants
PLA particles release their contents differently based on the type of fluorochrome used.
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research Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies
New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.
research The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research Seizure Control and Side-Effect Profile After Switching Adult Epileptic Patients from Standard to Extended-Release Divalproex Sodium
Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.
research Exogen Involves Gradual Release of the Hair Club Fiber in the Vibrissa Follicle Model
Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
research Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel from Human Hair-Derived Keratin Microparticle Carriers
Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism
The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
research Short-Term Efficacy and Safety of Valproate Sustained-Release Formulation in Newly Diagnosed Partial Epilepsy: VIPe Study. A Multicenter Observational Open-Label Study
Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
research Three Months Extended-Release Microspheres Prepared by Multi-Microchannel Microfluidics in Beagle Dog Models
A new device, IVL-PPF Microsphere®, was created to deliver a hair loss drug for up to 3 months with one injection, potentially replacing daily pills.
research Extracellular Vesicles Released from Irradiated Neonatal Mouse Cheek Tissue Increased Cell Survival After Radiation
Vesicles from irradiated mouse cheek skin help cells survive radiation.
research The Efficacy of Subcutaneous Slow-Release Melatonin Implants in the Prevention of Canine Flank Alopecia Recurrence Is Uncertain: A Double-Blind, Randomized, Placebo-Controlled Study
Melatonin implants did not effectively prevent hair loss in dogs.
research In Vitro Release of Zinc Pyrithione from a Shampoo Base and the Effects of Various Additives on Its Release Rate
Additives like ethanol and propylene glycol increase the release of zinc pyrithione from shampoo.
research Designing, Optimizing, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release Using Marine-Based Polymers
The new minoxidil emulgel with marine-based polymers shows effective controlled drug release for hair growth treatment.
research N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes
N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
research Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures
Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
research Androgen-Induced Norepinephrine Release in Male Accessory Sex Organ Smooth Muscle Growth and Differentiation
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 10 Days in Normal Men with Experimental Hypogonadism
research Promoted Growth of Murine Hair Follicles by Controlled Release of Growth Factors from Biodegradable Hydrogel
Using hydrogels to slowly release growth factors can effectively boost hair growth in mice.
research Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research Adult Stem Cell Released Molecules in Combination with Microneedling Restore Hair Growth
Combining stem cell molecules with microneedling improves hair growth.
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research Environmental Exposure to Platinum Group Elements Released by Automotive Catalytic Converters: The Risk for Children
Children are at risk of health issues from exposure to platinum group elements from car exhausts.
research Bee Venom Stimulates Growth Factor Release from Adipose-Derived Stem Cells to Promote Hair Growth
Bee venom can help stem cells promote hair growth.
research Combining Rapid Degrading Microneedles With Slow-Released Drug Delivery System for the Treatment of Alopecia Areata
A new microneedle patch treats hair loss effectively with fewer side effects and less frequent use.
research Detection of Lentiviral Constructs for Release Testing of CAR-T Cells Using Digital Droplet PCR
The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.
research Minoxidil Delivered Via a Stem Cell Membrane Delivery Controlled Release System Promotes Hair Growth in C57BL/6J Mice
A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.
research Effect of Hydroxypropyl Methylcellulose in Release Profile of Air Fresheners Gel Using Carrageenan and HPMC
The F2 Emulgel with Tridax procumbens extract showed good physical properties and antimicrobial effectiveness for wound healing.
research Evaluating Results of an Interferon-γ Release Assay in Patients With Autoimmune Skin Disease on Hydroxychloroquine
Hydroxychloroquine may cause false results in tuberculosis tests for patients with autoimmune skin diseases.
research Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells
Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
research Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation
Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.