Long-Term Suppression of Testosterone After Treatment With a Gonadotropin-Releasing Hormone Agonist in a Woman With a Presumed Testosterone-Secreting Ovarian Tumor

A 57-year-old woman presented with symptoms of androgen excess, including rapid hair growth and bilateral temporal balding, without voice deepening or increased libido. She had a history of chronic renal failure and was treated with prednisone for membranous glomerulonephritis. Physical examination revealed marked hirsutism and elevated testosterone levels. Despite no detectable ovarian masses, a gonadotropin-releasing hormone agonist was used to suppress testosterone levels, suggesting a presumed testosterone-secreting ovarian tumor. The treatment effectively reduced testosterone levels, alleviating symptoms of androgen excess.