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This study found that TRH modulates specific keratins in human scalp tissue, suggesting its potential influence on hair growth and the need for further exploration of neuroendocrine controls in keratin expression.

This study found that GnRH agonist treatment improved hirsutism scores more than finasteride after six months in women with idiopathic hirsutism, with both treatments causing no menstrual abnormalities or side-effects.

This report describes two cases of postmenopausal hyperandrogenism where GnRH analogue use suggested an ovarian source of excess androgens, leading to a diagnosis of benign ovarian tumors.

This study suggests that caribine may enhance the interaction between CRFR and maltose binding protein, potentially offering a new approach for treating hair loss.

This study found that GnRH-A treatment significantly reduced hirsuties scores in women with mild idiopathic hirsuties but did not affect hair growth rate or diameter.

This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.

This study found that corticotropin-releasing factor influences cytokine expression related to hair growth in human dermal papilla cells and suggests CRF receptor antagonists could be potential treatments for stress-induced hair loss.

In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.

This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.

Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.

This study found that stress-related hair loss may be driven by CRH-mediated mechanisms that inhibit autophagy and increase apoptosis in dermal papilla cells, suggesting potential therapeutic targets like PTEN activation or rapamycin to enhance autophagy.

In this study using mouse models, researchers found that stress-related hair loss may occur due to CRH-induced PTEN loss and inhibition of autophagy via the PI3K/AKT/mTOR pathway in dermal papilla cells, suggesting potential treatments through PTEN activation or autophagy enhancement.

This meta-analysis found that while both Dienogest and GnRH analogues effectively managed endometriosis-related pain, Dienogest reduced recurrence rates and hot flushes but increased irregular bleeding, making it a safer option due to fewer side effects.

In this study of a postmenopausal woman with hyperandrogenism, GnRH agonist treatment significantly reduced testosterone levels, suggesting the androgen excess was ovarian in origin and indicating the potential of using GnRH agonists as a conservative treatment option when surgery is not feasible.

This study found that recombinant type III collagen may aid skin aging management by promoting fibroblast proliferation and migration, with a modest impact on inflammatory marker IL-6, though it did not significantly affect TNF-a secretion in vitro.

This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.

TRH in hair follicles can influence hair color by increasing melanin.

This study used novel methods to detect and map iodine concentrations in pig skin, finding iodine present in the coating, stratum corneum, and tissue around hair follicles.

This study found that a nanoparticle-in-nanofiber system significantly accelerated wound healing in rats by promoting angiogenesis and tissue regeneration more effectively than a commercial wound dressing.

This study concluded that an endogenous circannual rhythm of prolactin secretion in mouflon influences their seasonal hair growth and moulting cycle, which varies under different photoperiodic and melatonin treatments.

This study found that using a protease-triggered release system enabled effective delivery of a model drug deep within porcine hair follicles, suggesting a new approach for treating skin conditions.

In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.

This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.

This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.

In this study, researchers developed a hyaluronic acid-coated copper peroxide nano-antimicrobial system that demonstrated precise antimicrobial activity and accelerated wound healing by releasing reactive oxygen species in response to bacterial enzymes, in both laboratory and animal tests.

In this study, researchers used a rodent model to uncover key changes in how hair fibers detach, suggesting that the exogen phase should be subdivided based on club fiber status.

This research highlights a hydrogel system that could significantly improve diabetic wound healing by releasing ibuprofen to both suppress inflammation and promote tissue regeneration, indicating a strong potential for future clinical use.

This study describes a method to extract and characterize keratin particles from human hair, finding they can encapsulate the anticancer drug Paclitaxel with significant efficiency, releasing it in a pH-dependent manner potentially beneficial for targeted cancer treatment.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

This study found that an oral testosterone formulation normalized serum testosterone levels and significantly reduced SHBG in men with experimentally induced hypogonadism after nine days of treatment, suggesting potential efficacy for testosterone deficiency.