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This source highlighted the promising potential of polynucleotides in aesthetic medicine but emphasized the need for rigorous, high-quality studies to validate their effectiveness and safety.

This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.

This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.

This study introduced laser-assisted exosome delivery and observed early signs of clinical improvement in two patients, though causality cannot be inferred from these preliminary, uncontrolled cases.

This review article highlights the potential of mesenchymal stem cells, their exosomes, and non-coding RNAs in repairing aging skin tissues due to their ability to secrete beneficial compounds, suggesting their promising role in photoaging treatment without causing immune rejection or granuloma formation.

This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.

In this review, several studies on Astragalus species, particularly Astragalus membranaceus, highlight their skin rejuvenating, photoprotective, antimicrobial, and wound-healing properties, though the authors note limitations due to reliance on non-human studies and short trial durations.

This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.

This study reviewed evidence suggesting that the loss of dermal white adipose tissue (dWAT) during menopause may be linked to decreased estrogen levels, potentially affecting skin health, and discussed non-hormonal treatments, like magnolol, that might help restore dWAT and improve menopausal skin changes.

This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.

In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.

This review synthesizes evidence on platelet-derived bioproducts like PRP and PRF, highlighting their role in tissue regeneration and their benefits in aesthetic medicine applications such as hair restoration, scar treatment, and wound healing.

In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This study found that self-noncoding dsRNA activates TLR3 to stimulate intrinsic retinoic acid synthesis, promoting new hair follicle formation in wounded mice and showing similar gene expression changes in humans treated with rejuvenation lasers.

In this exploration, the authors discuss the challenges and potential roles of aesthetic surgery in achieving long-lasting rejuvenation, touching on societal pressures linking beauty with youth and examining how modern techniques might offer a natural, subtle appearance despite the inevitability of aging.

This review concluded that Unani medicine offers a promising holistic approach to managing androgenetic alopecia by focusing on humoral balance and follicular rejuvenation, but further scientific validation is needed for widespread clinical use.

This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.

In this study involving adult mice, the researchers identified that double-stranded RNA-mediated activation of toll-like receptor 3 stimulates wound-induced hair neogenesis, potentially reflecting mechanisms used in facial rejuvenation treatments.

This study conducted among sex workers in Kostanay reported a low HIV prevalence of 0.8% but a high syphilis rate of 15.6%, highlighting significant social risks and emphasizing the need to expand pre-exposure prophylaxis and prevention programs.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This study examined dermal papilla cells from hair follicles, finding that gene expression changes linked to wound healing and stem cell activity align with hair follicle regression, which could inform strategies for hair growth and skin rejuvenation.

This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.

This study examined attractive white celebrities and found no significant difference in central forehead height between genders, but reported narrower and downward slanting foreheads in women, which may influence facial rejuvenation and gender-affirming surgery approaches.

This article outlines the importance for healthcare providers to understand skin histology and physiology before performing cosmetic procedures aimed at facial rejuvenation, categorized into four approaches: resurfacing, redraping, relaxing, and replacement/recontouring.

This review explores the skin benefits of exercise and discusses how artificial intelligence can tailor exercise programs to individual skin health needs, emphasizing the potential of AI-driven strategies in cosmetic dermatology for more personalized and adaptive skincare approaches.

This narrative review synthesizes findings suggesting that exosomes show promise for dermatological and regenerative applications, with early human studies indicating acceptable safety and potential benefits for wound care, rejuvenation, and alopecia, though clinical and regulatory development is still in its infancy.

This research observed that removing RNase L in mice enhances regenerative capacity through increased IL-36 and wound-induced hair neogenesis, highlighting RNase L as a gene that represses regeneration by moderating immune responses during viral infections.

This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.

This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.