Exosome-Based Therapeutics in Dermatology and Beyond: A Narrative Review

    February 2026 in “ MDPI (MDPI AG)
    Grant M. Pham
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    TLDR Exosome-based treatments may improve skin and hair issues, but more research is needed for safety and effectiveness.
    Exosome-based therapeutics show promise in dermatology for applications such as wound healing, photoaging, and hair disorders due to their ability to modulate inflammation, promote tissue regeneration, and influence hair growth pathways. Preclinical studies and early human trials suggest benefits like improved skin texture, faster wound healing, and hair growth stimulation, particularly when combined with procedures like microneedling and lasers. However, challenges such as product consistency, regulatory uncertainties, and the need for standardized protocols and larger controlled trials remain. While exosomes have potential as adjunctive treatments, more research is needed to confirm their efficacy and safety before they can be routinely integrated into clinical practice.
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