December 2025 in “Cosmetics” This review discusses recent advancements in the treatment of alopecia, focusing on alopecia areata (AA) and androgenetic alopecia (AGA). It highlights the role of immune and hormonal factors in these conditions and the potential of selective inhibitors like baricitinib and ritlecitinib to restore immune balance in AA. For AGA, the review emphasizes the impact of dihydrotestosterone on follicular miniaturization and the benefits of combination therapies, including low-dose oral minoxidil and platelet-rich plasma, in promoting hair regrowth. The paper also explores the significance of intracellular signaling pathways and the potential of stem cell organoids and exosome-based therapeutics in advancing treatment from mere suppression to structural follicle reconstruction. Additionally, it underscores the importance of maintaining microbial and mitochondrial homeostasis for effective and lasting hair regeneration.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
6 citations
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April 2023 in “Cosmetics” Exosomes could be effective for improving skin health and treating skin diseases.
10 citations
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September 2021 in “International Journal of Nanomedicine” Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
4 citations
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December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.