14 citations
,
January 2016 in “Experimental Dermatology” This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.
13 citations
,
March 2021 in “British Journal of Pharmacology” This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.
13 citations
,
July 2016 in “BMC Complementary and Alternative Medicine” In this study, topical application of Hominis Placenta significantly promoted hair regrowth and increased hair density in C57BL/6 mice, suggesting its potential as a treatment for alopecia.
11 citations
,
January 2009 in “Acta Dermato Venereologica” In this case report, a 37-year-old man with discoid lupus erythematosus experienced around 80% hair regrowth after treatment with a combination of oral and topical therapies.
9 citations
,
January 1992 in “Journal of Investigative Dermatology” This study found distinct differences in UEA I glycoprotein binding on follicular keratinocytes between anagen and telogen hair follicles, with staining associated with follicle length and regrowth.
7 citations
,
June 2019 in “Cureus” This literature review suggests that fractional lasers and microneedling, particularly when used with topical agents, may be effective treatments for alopecia areata; however, the small size and number of studies highlight a need for larger trials to confirm efficacy.
4 citations
,
May 2021 in “Lasers in Surgery and Medicine” This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.
4 citations
,
April 2021 in “Journal of Cosmetic Dermatology” This study found that both intradermal injection and derma roller techniques for QR678Neo® hair regrowth therapy improved androgenetic alopecia symptoms, with intradermal injections showing non-significantly better video-microscopic outcomes but more pain and erythema associated with derma rollers.
4 citations
,
March 2019 in “Experimental Biology and Medicine” This study found that exposure to 50 Hz electromagnetic fields enhanced hair regrowth in mice by increasing stem cell proliferation and keratinocyte growth factor expression, suggesting potential benefits for hair loss treatment.
1 citations
,
July 2020 in “Bezmialem science” This study found that reflexology massage significantly improved hair regrowth in women with chemotherapy-induced alopecia compared to those receiving usual care.
1 citations
,
April 2017 in “Journal of Dermatology and Dermatologic Surgery” This case report describes two patients who experienced significant hair growth after receiving intravenous immunoglobulin treatments, but it provides no new findings on using this treatment for androgenic alopecia.
July 2026 in “Frontiers in Pediatrics” In this case study, an 11-year-old girl with severe alopecia areata experienced complete hair regrowth and unexpected white-to-black hair repigmentation after switching from baricitinib to ritlecitinib, suggesting that prolonged Janus kinase inhibition may aid both hair and pigment restoration in severe pediatric cases.
In this randomized, double-blind study of 24 participants with hair loss, the combination of bromelain and finasteride increased hair count, thickness, and density significantly more than finasteride alone or a placebo cream, while reducing inflammatory markers.
October 2023 in “Frontiers in medicine” Targeted immunotherapy could be a promising new treatment for hair regrowth.
This case report describes a 21-year-old man with alopecia areata presenting as a U-shaped hair loss pattern resembling Hamilton grade VII male-pattern baldness, with no signs of inflammation or related conditions.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” This study found that in transgenic mice overexpressing a mutant hairless gene, changes in its expression affected hair loss and regrowth, implicating the gene's role in hair follicle biology.
196 citations
,
September 2016 in “JCI insight” This study explored the effectiveness of the oral JAK1/2 inhibitor ruxolitinib in treating patients with moderate-to-severe alopecia areata, building on prior success with JAK inhibitors in mice, but results are not reported in this abstract.
July 2025 in “Journal of Case Reports and Scientific Images” This study reports that a patient with severe, treatment-resistant alopecia areata experienced sustained hair regrowth and emotional improvement over 24 months following individualized homeopathic treatment, suggesting homeopathy may be a viable therapeutic option when conventional treatments fail.
51 citations
,
May 2011 in “Phytotherapy Research” This study suggests that red ginseng rhizome extracts, particularly ginsenoside Ro, may promote hair re-growth in an androgenetic alopecia model due to their inhibitory activity on testosterone 5α-reductase.
23 citations
,
January 2021 in “Biomedicine & Pharmacotherapy” This study found that dihydrotestosterone induced hair loss and changes in hair morphology in male C57BL/6 mice, effects that could be partially reversed by the AR antagonist bicalutamide.
23 citations
,
April 2002 in “Journal of the American Academy of Dermatology” This case report describes persistent depigmented hair regrowth from an alopecia areata patch, challenging the previous assumption that such regrowth is only temporary.
8 citations
,
September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
June 2024 in “Frontiers in pharmacology” This study found that a 2-deoxy-D-ribose gel stimulated hair follicle growth in mice with androgenic alopecia, showing effects similar to minoxidil without additional benefits from combining the two treatments.
November 2020 in “Journal of The American Academy of Dermatology” This case report highlights that patients with long-standing alopecia areata treated with oral JAK inhibitors experienced unexpected hair regrowth patterns resembling male-pattern baldness.
70 citations
,
April 2016 in “Experimental Dermatology” In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.
7 citations
,
January 2017 in “Journal of cosmetology & trichology” This article discusses how nutritional and environmental factors, along with antioxidant supplementation, may improve hair growth by mitigating the effects of androgens and reports no new clinical results.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
September 2025 in “International Journal of Science and Research (IJSR)” This theoretical review analyzes how stress affects hair loss through hormonal and neural pathways, indicating that knowledgeable hairdressers could help in early detection and guide clients toward medical interventions, highlighting a potential collaboration between aesthetic care and medical treatment for stress-induced alopecia.
January 2017 in “International journal of clinical & experimental dermatology” This review discusses how nutritional and lifestyle modifications, including antioxidant use, may enhance hair growth and prevent hair loss without the need for Finasteride, but provides no new clinical findings.