Successful Hair Regrowth with Multimodal Treatment of Early Cicatricial Alopecia in Discoid Lupus Erythematosus

    January 2009 in “ Acta Dermato Venereologica ”
    Trevor D. Hamilton, Nina Otberg, Wu Wy, Michal Martinka, J Shapiro
    TLDR Early and aggressive treatment can significantly regrow hair in discoid lupus erythematosus.
    In this 2009 case report, a 37-year-old man with early cicatricial alopecia due to discoid lupus erythematosus (DLE) experienced significant hair regrowth following an aggressive multimodal treatment regimen. The treatment included oral prednisone, hydroxychloroquine, topical clobetasol, topical tacrolimus, and intralesional triamcinolone acetonide injections. After 4 months, approximately 80% hair regrowth was observed, and no further progression of scalp lesions was detected. This case highlighted the importance of early and aggressive treatment in preventing irreversible hair loss in DLE.
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