Psychophysiological Mechanisms of Stress Impact on Hair Loss Processes
September 2025
in “
International Journal of Science and Research (IJSR)
”
stress-induced hair loss neuroendocrine pathways neurogenic pathways molecular pathways cellular pathways CRH corticotropin-releasing hormone ACTH adrenocorticotropic hormone cortisol hair growth cycles thinning shedding graying NK-1R inhibitors neurokinin-1 receptor inhibitors JAK inhibitors Janus kinase inhibitors antioxidants aesthetic care alopecia stress-induced alopecia hair thinning hair shedding hair graying
TLDR Stress causes hair loss by disrupting hair growth cycles, and combining medical and cosmetic treatments can help manage it.
The article reviews how stress induces hair loss through neuroendocrine, neurogenic, molecular, and cellular pathways, involving hormones like CRH, ACTH, and cortisol, which disrupt hair growth cycles and lead to thinning, shedding, and graying. It discusses therapeutic interventions such as NK-1R inhibitors, JAK inhibitors, and antioxidants, suggesting their integration into aesthetic care. Hairdressers are highlighted as key in early detection and referral for medical evaluation. The study emphasizes the need for combined medical and cosmetic treatments and calls for future research on collaborative protocols between hair professionals and medical specialists to improve prevention and treatment of stress-induced alopecia.
