68 citations
,
March 2018 in “Biomaterials” This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.
61 citations
,
June 2014 in “Scientific Reports” This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.
36 citations
,
April 2016 in “Experimental Dermatology” This review discusses the challenges in selecting optical parameters for photobiomodulation studies on hair regrowth and wound healing, reporting no new clinical results and recommending more rigorous, standardized research approaches.
14 citations
,
June 2019 in “Dermatologic therapy” This study found that autologous platelet-rich plasma injections showed no significant effect on hair regrowth in patients with alopecia areata totalis.
6 citations
,
October 2000 in “International Journal of Dermatology” This article discusses the importance of focusing on prevention rather than regrowth in managing male pattern hair loss but reports no new clinical results.
6 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” In this study, fermented herbal extracts promoted hair growth and activated Wnt signaling more effectively than nonfermented extracts in mice, suggesting potential benefits for hair regrowth.
5 citations
,
April 2019 in “Plastic and reconstructive surgery. Global open” This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.
3 citations
,
June 2018 in “Australasian journal of dermatology” This letter reports eight cases of spontaneous hair regrowth in patients with severe alopecia areata.
2 citations
,
November 1998 in “Journal of The European Academy of Dermatology and Venereology” This article reports on a partial regrowth of scalp hair in a patient treated with extracorporeal photochemotherapy and interferon α 2a, but provides no new clinical outcomes.
May 2026 in “Frontiers in Pharmacology” In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.
May 2025 in “LUMEN ET VIRTUS” This study reports that perioperative nursing care for hair transplant patients improves outcomes by reducing complications and enhancing patient satisfaction, emphasizing the crucial role of nurses in managing the procedure.
September 2018 in “The Medical Journal of Cairo University/The Medical Journal of Cairo University” In this study, polarized light therapy increased hair regrowth in patients with alopecia areata compared to those who received only minoxidil.
May 2014 in “Transfusion and Apheresis Science” PRP treatment showed no hair regrowth improvement after the first application in patients with alopecia.
March 2021 in “British Journal of Dermatology” This study using a humanized mouse model of androgenetic alopecia suggests that platelet-rich plasma may promote hair regrowth and improve hair characteristics in vivo.
75 citations
,
August 2003 in “International journal of cosmetic surgery and aesthetic dermatology” This study found that low level laser therapy with a HairMax LaserComb improved hair counts and tensile strength in patients with androgenetic alopecia, particularly in males and vertex areas.
14 citations
,
January 2016 in “Biochemical and Biophysical Research Communications” In this study, researchers found that ginsenoside Re from Panax ginseng increased hair shaft length and duration in mice, comparable to minoxidil, by modulating TGF-β signaling pathways.
November 2024 in “Journal of Translational Internal Medicine” This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.
192 citations
,
April 2019 in “ACS nano” In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
118 citations
,
April 1998 in “Dermatologic Clinics” This review discusses the advancements in understanding and treating androgenetic alopecia and alopecia areata but reports no clinical findings; the authors emphasize the need for further research on molecular control mechanisms.
81 citations
,
July 2011 in “Lasers in Medical Science” This study found that using a low-level laser comb led to hair regrowth in a mouse model of alopecia areata, while sham-treated mice showed no hair regrowth.
60 citations
,
December 2015 in “Lasers in Medical Science” This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.
53 citations
,
November 2006 in “Journal of Endocrinology” This study found that prolactin plays a direct role in regulating the timing of hair growth cycles in mice by affecting the skin, rather than through other endocrine factors.
43 citations
,
June 2012 in “Lasers in Medical Science” In a rat model of chemotherapy-induced alopecia, this study found that low-level laser treatment significantly accelerated hair regrowth without affecting the efficacy of chemotherapy.
39 citations
,
December 2001 in “JNCI: Journal of the National Cancer Institute” This study found that enhanced expression of the Sonic hedgehog gene via an adenovirus vector accelerated hair regrowth in mice with chemotherapy-induced alopecia.
24 citations
,
January 2020 in “JAAD Case Reports” This article discusses the staging of central centrifugal cicatricial alopecia in women of African descent and reports no new clinical results.
20 citations
,
February 2004 in “Veterinary dermatology” This study found that the season of the year does not significantly affect the hair regrowth rate or the telogen: anagen ratio in indoor-housed Labrador retrievers.
20 citations
,
December 2015 in “Journal of Pharmacopuncture” In this study, thread-embedding therapy enhanced hair regrowth in C57BL/6 mice by regulating growth factors associated with hair follicle anagen development and promoting cellular proliferation in hair follicles.
20 citations
,
February 1985 in “Archives of Dermatology” This report discusses the potential of minoxidil for treating hair loss, spurred by early findings of hair regrowth in some patients, but emphasizes the need for further research to establish its safety and efficacy.
17 citations
,
January 2006 in “Veterinary Dermatology” This study found that topical melatonin and vigorous brushing did not affect hair regrowth in clipped Siberian Huskies, although lumbosacral hairs grew significantly shorter than lateral thigh hairs.
17 citations
,
February 2018 in “Journal of Cosmetic and Laser Therapy” In this study, researchers administered eight sessions of intradermal injections containing growth factors into the scalp of 1000 patients, reporting a significant reduction in hair fall in 83% of participants and increased total hair count and shaft diameter, with promising tolerance and safety.