23 citations
,
June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
21 citations
,
November 2012 in “Plastic and Reconstructive Surgery” The researchers reported that various environmental factors and higher testosterone levels were linked to different patterns of hair loss in women with androgenic alopecia.
21 citations
,
January 2003 in “Skin pharmacology and physiology” This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.
21 citations
,
May 1988 in “Journal of The American Academy of Dermatology” This article reviews the challenges of providing dermatology care in prisons and reports no new clinical findings, highlighting common skin conditions like tinea pedis, pruritus, and alopecia areata linked to stress and the environment.
20 citations
,
December 2012 in “Journal of molecular structure” This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.
20 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” This review focuses on the medical treatment of common nonscarring alopecias, including androgenetic alopecia, alopecia areata, and telogen effluvium, and reports no new clinical results.
19 citations
,
October 2009 in “Bioorganic & Medicinal Chemistry Letters” This study found that a thyroid hormone receptor ẞ subtype-selective thyromimetic was effective in promoting hair growth in mouse and monkey models when applied topically.
18 citations
,
July 2020 in “Basic and Clinical Andrology” This article discusses concerns and recommendations from a French-speaking andrology society regarding COVID-19's potential impact on men's reproductive health and calls for further research in this area.
18 citations
,
April 1986 in “International Journal of Cosmetic Science” In this study with stumptailed macaques, topical minoxidil successfully induced hair regrowth on bald scalps and prevented baldness on non-bald scalps, with no observed side effects over nearly three years.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
14 citations
,
January 2019 in “Skin appendage disorders” This paper discusses the first reported case of post-finasteride syndrome in a long-term dermatotrichology setting, occurring in a 25-year-old male after dutasteride treatment, and highlights possible links to mental health disorders.
14 citations
,
January 2013 in “International Journal of Trichology” This review discusses physician-patient dynamics in managing hair loss and highlights the emotional impacts, emphasizing the need for effective communication and patient education, but it reports no new clinical findings.
14 citations
,
December 2011 in “Archives of Dermatological Research” This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.
14 citations
,
February 2011 in “Drug Metabolism and Disposition” This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
12 citations
,
April 1995 in “Journal of Medicinal Chemistry” In this study, 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides were synthesized and evaluated in vitro as potential 5 alpha-reductase inhibitors and antiandrogens.
10 citations
,
June 2019 in “International Journal of Cosmetic Science” This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.
10 citations
,
May 2018 in “Nutrition and Cancer” This article reviews current research on spice-derived nutraceuticals for treating melanoma and skin cancer, noting emerging evidence that these natural substances may offer preventative and protective benefits against cancer, amidst increased global interest.
10 citations
,
January 2008 in “Biological and Pharmaceutical Bulletin” This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.
9 citations
,
April 2017 in “International Journal of Dermatology” This study found significant differences in hair diameter between males and females across different zones of the safe donor area, which may aid in selecting optimal donor regions for hair transplantation surgeries.
9 citations
,
August 2014 in “Journal of The American Academy of Dermatology” This article discusses the authors' concerns over the misinterpretation of studies linking smoking and frontal fibrosing alopecia, clarifying that neither study suggests smoking is protective against the condition.
9 citations
,
August 2013 in “PLOS ONE” This study validated that the 20p11 genetic locus is associated with increased risk of androgenic alopecia in the Chinese Han population, suggesting shared genetic factors between Chinese and European populations.
9 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” This report documents the second known case of Castleman's disease in the lacrimal gland, diagnosed in an 84-year-old woman through histological examination after excising a left upper lid mass.
9 citations
,
January 1987 in “Journal of The American Academy of Dermatology” This study supports the idea that angiolymphoid hyperplasia with eosinophilia is an inflammatory process linked to immunologic injuries rather than a proliferative condition.
8 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This report describes nine women who were allergic to topical minoxidil but successfully tolerated low-dose oral minoxidil without significant adverse effects, suggesting it may be a viable alternative for those with similar allergies.
8 citations
,
January 2017 in “Methods in molecular biology” This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.
8 citations
,
January 2016 in “Annals of Dermatology” This study found that the ALAVAX complex, containing 5-ALA and GHK peptide, may increase hair count in male pattern hair loss patients over 6 months without adverse events.
8 citations
,
January 2013 in “Journal of The Korean Medical Association” This article reviews factors influencing hair growth and treatment options for androgenetic alopecia, but it reports no new clinical results on their effectiveness.
7 citations
,
June 2021 in “Trends in Food Science and Technology” This commentary reviews potential dietary and mineral influences on androgenetic alopecia and suggests considering a diet low in cholesterol and glycaemic index with improved glucose control and magnesium fortification, without new clinical results.
7 citations
,
July 2018 in “Biological & Pharmaceutical Bulletin” This study found that Phyllanthus urinaria extract displayed significant anti-alopecia properties in a mouse model, showing potential as an anti-5α-reductase agent for androgenic hair loss.
6 citations
,
March 2018 in “Journal of Medicinal Food” This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.