March 2023 in “Human Pathology” This review found that while follicular hair counts and ratios assist in diagnosing non-scarring alopecia, they should be used alongside specific morphological features for accurate diagnosis.
57 citations
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January 2022 in “Biomedicines” This review outlines curcumin's dual role as a radiosensitizer in cancer cells and a radioprotector in healthy cells, drawing on recent experimental and clinical findings.
23 citations
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March 1998 in “Dermatologic Surgery” This narrative discusses the use of radiosurgery in cosmetic procedures and reports no new clinical results.
7 citations
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September 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that the ovarian stromal area to total ovarian area ratio alone is not a strong predictor of biochemical hyperandrogenism in Thai women with PCOS, but combining it with clinical hyperandrogenism improves prediction.
4 citations
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August 2017 in “Journal of Cosmetic Dermatology” The study found that males with androgenetic alopecia had a significantly lower left-hand 2D:4D digit ratio compared to healthy controls, suggesting this ratio may help estimate future AGA risk.
2 citations
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December 2024 in “PLoS ONE” This study found that patients with alopecia areata exhibited higher ratios of neutrophils-to-lymphocytes and eosinophils-to-lymphocytes compared to controls, suggesting potential markers for disease prediction and management.
January 2026 in “Scientific Reports” This study found that among pediatric patients with alopecia areata, elevated eosinophilic hematological ratios were observed, suggesting these could serve as markers for disease exacerbation and the pathophysiology of the condition.
November 2025 in “Scientific Reports” This study demonstrates that an AI-based grading framework using a novel area ratio metric improves the accuracy and consistency of male pattern hair loss classification, especially in advanced grades, compared to traditional methods.
November 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that among vitiligo patients in south-southern Nigeria, there were significant correlations between digit lengths and digit ratio, but further research is needed due to the small sample size.
March 2021 in “Juniper Online Journal Material Science” In this study, L-cysteine treated with the Trivedi Effect® showed significantly increased isotopic abundance ratios, which may enhance its stability and shelf-life.
1 citations
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January 2024 in “Annals of Dermatology” This study suggests that analyzing microscopic hair morphology, particularly loss of typical clubbing and proximal tapering, may help predict the clinical course of alopecia areata.
December 2022 in “The Aging Male” This study found that in male patients, a lower right-handed 2D:4D digit ratio combined with older age correlated with increased severity risk of androgenetic alopecia.
55 citations
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March 1990 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.
19 citations
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February 2013 in “The American Journal of Dermatopathology” This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.
8 citations
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April 2016 in “Anais Brasileiros De Dermatologia” This study found that males with androgenetic alopecia had a significantly lower 2D:4D digit length ratio in the right hand compared to healthy controls, which may indicate prenatal androgen exposure.
5 citations
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May 2019 in “Anais Brasileiros de Dermatologia” This article discusses the connection between prenatal androgen exposure, marked by the second-to-fourth digit ratio, and seborrheic dermatitis, but reports no new experimental findings.
3 citations
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February 2019 in “Disease Markers” This study reports that a lower 2D:4D finger length ratio is significantly associated with higher disease activity and reduced spinal mobility in females with ankylosing spondylitis, but not in males.
3 citations
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November 2018 in “The Journal of Clinical Psychiatry” This study discusses the difficulties in interpreting and communicating the association of 5α-reductase inhibitors with impaired libido and erectile dysfunction in men with benign prostatic hyperplasia due to the use of odds ratios instead of relative risks.
3 citations
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June 2016 in “Dermatology Reports” This study concluded that the digit-length ratio (2D:4D) does not predict androgenic alopecia development, suggesting prenatal androgen exposure does not predispose men to this condition.
2 citations
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July 2022 in “Dermatology practical & conceptual” In this study, researchers found that women with telogen effluvium had lower MCV/RDW ratios, MPV, and ferritin levels compared to healthy controls, suggesting iron deficiency's involvement in this chronic hair loss condition.
1 citations
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October 2025 in “EBioMedicine” Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.
1 citations
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January 2021 in “Open Access Journal of Cancer & Oncology” In this study, the Trivedi Effect®-Consciousness Energy Healing Treatment was reported to significantly increase the solubility and isotopic abundance ratios of flutamide, potentially improving its stability and efficacy.
In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.
November 2025 in “BMC Endocrine Disorders” This study found that in PCOS patients, a lower TT/DHT ratio is associated with regular menstruation, while higher ratios are linked to insulin resistance, suggesting its potential as a biomarker for metabolic severity in these patients.
September 2025 in “British Journal of Hospital Medicine” This study found that certain plasma protein ratios, specifically AGRN/HSPG2 and DECR1/FKBP1B, were significantly associated with an increased risk of alopecia areata, indicating potential causal relationships but reverse causality was not supported.
September 2024 in “Turkish Journal of Dermatology” In this study, researchers found that males with alopecia areata had a significantly lower 2D to 4D finger length ratio compared to healthy controls, suggesting this ratio might predict alopecia areata development, though it did not correlate with disease severity.
October 2023 in “Dermatology practical & conceptual” In this review, the authors evaluated the potential of using the second to fourth digit ratio (2D:4D) as a predictor for androgenetic alopecia, suggesting future research directions but not reporting definitive results.
January 2021 in “Turkiye Klinikleri Journal of Dermatology” In this study, the MPV/PC ratio was identified as a potential tool for assessing disease activity in alopecia areata, with higher ratios in active and severe cases compared to inactive and mild/moderate ones.
February 2019 in “Obstetrics and gynaecology cases - reviews” This study compared hirsutism levels, hand measurements, testosterone, and DHEAS levels in women aged 18 to 38 but does not report new definitive findings.
June 2018 in “Biomedical Journal of Scientific and Technical Research” In this study, a significant negative correlation was observed between the 2D:4D digit ratio and maxillary sinus volume in men, suggesting an androgenic hormone influence on sinus volume development.