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Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Finasteride may affect PNMT, causing side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

High doses of finasteride cause cell growth and tumors in mice.

Some herbs show promise as antiandrogenic agents.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Compounds from the plant Mammea siamensis may help treat hair loss.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Certain drugs change freshwater snail shells to a "banana" shape.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Finasteride doesn't affect sleep spindles in men.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Licorice extract helps hair growth and may treat hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.