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This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.

This study found that ultra-pulse CO2 fractional laser treatment improved skin smoothness and total skin lesion scores more effectively in patients with depressed acne scars compared to other treatments.

This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.

This study found that pentoxifylline plus topical corticosteroids had the highest treatment success rate for alopecia areata compared to no treatment, but the best overall treatment remains uncertain due to varying data.

This study found that total testosterone and free testosterone are recommended as first-line tests for diagnosing biochemical hyperandrogenism in women with PCOS; liquid chromatography with tandem mass spectrometry is preferred for its accuracy.

This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.

This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.

This study reported that neuropathic pain is prevalent in 6.7% of hospitalized COVID-19 patients during the acute phase and 34.3% of long COVID patients, highlighting the need for additional research.

This study found that local platelet-rich plasma injection improved mid-term outcomes for carpal tunnel syndrome more effectively than other conservative treatments, although long-term effects and standardization need further research.

This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.

This study found no significant difference in the severity of alopecia areata between treatments with platelet-rich plasma and triamcinolone acetonide; further high-quality trials of PRP are needed.

This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.

This study showed that knocking out the Ppp2ca gene in the epidermis of mice led to significant hair loss and disrupted hair follicle morphogenesis and regeneration.

This meta-analysis reports that trastuzumab deruxtecan is effective and has an acceptable safety profile for treating HER2-low or positive advanced breast cancer, although further research is recommended to support individualized treatment strategies.

This study found evidence that atopic dermatitis may increase the risk of developing rheumatoid arthritis, type 1 diabetes, and alopecia areata, but not other autoimmune diseases.

This study suggests that testosterone therapy in AFAB individuals may modify the methylation of the ESR2 promoter, with changes influenced by factors like total testosterone levels and age.

This study reported that Longdan Xiegan decoction is more effective than conventional western medicine alone in treating eczema, but the evidence quality was generally low, highlighting the need for further studies.

This meta-analysis found that the rs2476601 SNP of the PTPN22 gene is significantly associated with reduced susceptibility to alopecia areata, with carriers of the C-allele and CC-genotype having a lower risk.

This study explores the potential connection between circulating cytokines and immune skin diseases, offering insights that may enhance understanding of their causes, diagnosis, and treatment approaches.

This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.

This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.

This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.

Vitamin D and zinc may help treat alopecia areata.

This review discusses the challenges in diagnosing PCOS in adolescents due to overlapping symptoms with normal puberty and reports no new clinical findings, emphasizing the need for more research on treatment options.

This meta-analysis suggests that certain VEGF gene polymorphisms may be linked to polycystic ovary syndrome risk, potentially serving as early detection biomarkers.

This study found a causal relationship between type 1 diabetes and autoimmune disorders such as SLE, RA, and MS in Europe, but not between T1DM and SLE in East Asia, highlighting the need for preventive monitoring in affected regions.

This meta-analysis found that women with polycystic ovary syndrome have over a 2.5-fold higher risk of depression compared to healthy women.

This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.

This review discusses the structure and function of the testes in male reproduction and development, noting the complex hormonal regulation within the hypothalamic-pituitary-gonadal axis but reports no new clinical results.

This study found that people with alopecia areata have a higher likelihood of experiencing anxiety and depression, and a moderate negative impact on their quality of life compared to healthy individuals.