Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
May 2016
in “
International Journal of Molecular Sciences
”
Research cited in this study
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The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
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The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
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Hair and nail cells share similar proteins, indicating a common differentiation pathway.