Evaluating the Diagnostic Accuracy of Androgen Measurement in Polycystic Ovary Syndrome: A Systematic Review and Diagnostic Meta-Analysis to Inform Evidence-Based Guidelines

    September 2024 in “ Human Reproduction Update ”
    Asmamaw Demis, Anju E. Joham, Helena Teede … Chau Thien Tay
    Studysummary This study found that total testosterone and free testosterone are recommended as first-line tests for diagnosing biochemical hyperandrogenism in women with PCOS; liquid chromatography with tandem mass spectrometry is preferred for its accuracy.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on academic.oup.com →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome The Journal of Clinical Endocrinology and Metabolism · 2023
    2. Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review Egyptian Journal of Medical Human Genetics · 2019
    3. Polycystic Ovary Syndrome: Comprehensive Overview Obstetrics & Gynecology · 2018
    4. Hyperandrogenemia in Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Association with Body Mass Index Hormone Molecular Biology and Clinical Investigation · 2017
    5. Prostate Specific Antigen in Diagnosis of Polycystic Ovarian Syndrome: A New Insight Gynecological Endocrinology · 2016
    6. American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1 Endocrine Practice · 2015
    7. Clinical Biochemistry of Dihydrotestosterone Annals of Clinical Biochemistry · 2013
    8. Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan BMC Medicine · 2010
    9. Prevalence of Hyperandrogenemia in Polycystic Ovary Syndrome Diagnosed by the National Institutes of Health 1990 Criteria Fertility and Sterility · 2009
    10. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    11. Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline The Journal of Clinical Endocrinology and Metabolism · 2006
    12. Is It Necessary to Measure Free Testosterone to Assess Hyperandrogenemia in Women? The Role of Calculated Free and Bioavailable Testosterone Experimental and Clinical Endocrinology & Diabetes · 2006
    13. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    14. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003
    15. Receiver Operating Characteristic Analysis of the Performance of Basal Serum Hormone Profiles for the Diagnosis of Polycystic Ovary Syndrome in Epidemiological Studies European journal of endocrinology · 2001

    Related research 4

    1. Current Aspects of Polycystic Ovary Syndrome: A Literature Review Revista Da Associacao Medica Brasileira · 2016
    2. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    3. The Diagnosis of Polycystic Ovary Syndrome in Adolescents American Journal of Obstetrics and Gynecology · 2010
    4. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004